14 citations
,
June 2013 in “Anais Brasileiros de Dermatologia” This report found follicular red dots in patients with scalp pigmentary disorders, suggesting they might be linked to the scalp's vascular structure and may have implications for conditions like discoid lupus erythematosus.
47 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This review examines the pathogenesis of premature hair graying and potential treatment avenues, but reports no new experimental outcomes, highlighting ongoing research challenges and hopes for drug development.
38 citations
,
February 2002 in “British journal of dermatology/British journal of dermatology, Supplement” This report describes two cases of sustained hair repigmentation related to porphyria cutanea tarda, though the underlying mechanism remains unclear.
12 citations
,
November 1945 in “Archives of dermatology” In this study, hair color changes in piebald rats after skin grafting suggest that such changes are more likely due to the surgical process than the new environment.
1 citations
,
March 2024 in “Life” In this study, researchers identified specific clinical and dermoscopic features of chronic radiation-induced dermatitis in 32 head and neck cancer patients treated with radiotherapy, and determined age, gender, and prior surgery as independent risk factors for developing this skin toxicity.
8 citations
,
May 2012 in “Clinical and Experimental Dermatology” This article discusses a case of sudden hair whitening in an 82-year-old woman, exploring the 'overnight greying' phenomenon, and reports no new results.
35 citations
,
December 2014 in “Lasers in surgery and medicine” This study found that red light accelerated the transition from the resting to growth phase in hair follicles faster than green and blue light in mice, suggesting it may stimulate hair growth.
3 citations
,
May 2010 in “Archives of dermatology” This excerpt discusses website navigation and access details for JAMA Dermatology and reports no new research findings.
13 citations
,
March 1983 in “International Journal of Dermatology” Minoxidil caused red hair to grow on a man's temples.
8 citations
,
August 2015 in “Journal of dermatological science” This study observed that the topical skin-whitening agent rhododendrol induced skin depigmentation in approximately 16,000 consumers, linked to melanocyte cytotoxicity and immune reactions.
January 2017 in “프로그램북(구 초록집)” This report describes a case of acquired trichorrhexis nodosa in a woman with severe iron deficiency anemia, highlighting a possible link between the two conditions.
2 citations
,
March 2017 in “Sultan Qaboos University medical journal” This case report describes a six-month-old infant with focal scalp hair heterochromia and no detectable underlying abnormalities, which was still present at a one-year follow-up.
6 citations
,
January 1988 in “PubMed” This case report describes a woman who developed green hair due to high copper levels in swimming pool water, exacerbated by hair treatments and inadequate water replacement.
16 citations
,
February 2008 in “PubMed” Vitamin B12 deficiency can cause skin darkening and white hair, but it's reversible.
February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that certain tandem repeats predict darker hair color across diverse ancestry groups and can contribute to a polygenic score for hair color, independent of SNP variation.
25 citations
,
March 2012 in “Journal of oncology pharmacy practice” This case report describes an elderly multiple myeloma patient whose hair repigmentation was associated with lenalidomide use, suggesting hair graying may be reversible.
April 2024 in “Communications biology” The researchers reported that disrupting ATRA signaling by deleting RDHE genes in the hair follicle led to altered hair follicle cycles, composition, and gene expression, indicating RDHEs' role in hair follicle signaling coordination.
15 citations
,
March 1997 in “International Journal of Dermatology” In this case report, the authors describe green hair discoloration in a patient attributed to the use of selenium sulfide.
21 citations
,
December 2023 in “Journal of Investigative Dermatology” This study highlights multiple factors contributing to hair graying, such as oxidative damage, melanocyte changes, and genetic influences, and suggests that repigmentation may be temporarily reversible, offering potential targets for future treatments while urging caution when applying mouse model findings to humans.
April 2017 in “Journal of Investigative Dermatology” This study found that anagen hair follicles can quickly regenerate after radiation damage by forming new progenitor cells outside the bulge, bypassing the need for telogen entry.
17 citations
,
January 2015 in “Dermatology online journal” This report describes a patient experiencing hair repigmentation linked to adalimumab therapy, a TNF inhibitor, a phenomenon not previously associated with this class of drugs.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Iron deficiency is not more common in women with hair loss, and neurogenic rosacea may need different treatment.
December 2014 in “Bali Medical Journal” This study observed that estrogen receptor content was lower in white hair compared to black hair, with the lowest levels recorded in male white hair among participants aged 50-56.
2 citations
,
March 2023 in “JAAD case reports” This case report describes the unexpected hair repigmentation surrounding a scalp tumor in a 74-year-old man, suggesting a potential link between the carcinoma and changes in hair pigmentation.
8 citations
,
January 2013 in “Annals of Dermatology” This study found that hair dyeing is more common among Korean women than men and among individuals with significant grayness, and it was not linked to higher scalp disease prevalence.
June 2025 in “Bioinformation” This study found that nearly one in four young adults in a dermatology clinic had premature greying of hair, influenced by genetic factors, lifestyle, and micronutrient levels.
This study found that some white or grey hairs can naturally regain pigmentation, suggesting hair greying may be reversible in certain conditions linked to psychological stress.
11 citations
,
August 1986 in “Archives of Dermatology” This case report describes a patient with skin and nail hyperpigmentation and premature gray hair due to vitamin B12 deficiency, which were reversed after treatment with cyanocobalamin.
46 citations
,
April 2014 in “PLOS ONE” This study found that compromised antioxidant activity in gray hair follicles affects both mature melanocytes and their immature precursors, linked to down-regulation of melanogenesis-related genes.
April 2025 in “Turkish Journal of Hematology” Nilotinib may cause gray hair to return to its original color.