1 citations
,
September 2016 in “Journal of Dermatological Science” This study found that FGF18 signaling helps protect hair follicles from radiation damage by maintaining the resting phase and supporting stem cell survival, potentially reducing radiation-induced hair loss.
14 citations
,
January 2013 in “Journal of Cutaneous Medicine and Surgery” This study describes permanent scalp alopecia in patients receiving chemotherapy, radiation, or both, and highlights the need for further research to identify causative factors and mitigation strategies.
13 citations
,
January 2014 in “Dermatology” This study reported that alopecic lesions after radiation exposure during angioembolization share dermoscopic features with alopecia areata, highlighting the importance of accurate patient history to avoid misdiagnosis.
37 citations
,
February 2008 in “PubMed” This article reviews radiation-induced cicatricial alopecia and suggests that controlling radiation dose depth could potentially prevent this condition.
June 2025 in “Clinical Cosmetic and Investigational Dermatology” In this case report, a 42-year-old man with radiation-induced alopecia following endovascular embolization for a cerebral arteriovenous fistula experienced complete hair regrowth after three months of treatment with intramuscular corticosteroids and topical 5% minoxidil, suggesting a novel therapeutic approach for faster recovery.
28 citations
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June 2012 in “International Journal of Molecular Medicine” This study observed that while X-ray radiation did not alter major hair keratin composition in mice, it decreased hair follicle stem cell markers and increased Krt5, suggesting potential as a radiation biomarker.
24 citations
,
August 2020 in “JAMA dermatology” In this study, researchers observed a dose-dependent occurrence of persistent radiation-induced alopecia in patients with primary CNS tumors or head and neck sarcomas, noting distinctive patterns and features, and suggesting potential benefits of topical minoxidil and procedural interventions for treatment.
19 citations
,
November 2015 in “Radiation Oncology” This study found that hippocampus sparing whole brain radiation therapy (HS-WBRT) using multi-field intensity modulated radiation therapy prevents alopecia without compromising cognitive function compared to traditional whole brain radiation therapy.
17 citations
,
January 2010 in “International journal of trichology” This case report highlights the occurrence of radiation-induced alopecia in a patient undergoing radiotherapy for oropharyngeal carcinoma, emphasizing awareness of this potential side effect.
10 citations
,
October 2014 in “Plastic & Reconstructive Surgery Global Open” In this case study, Botulinum toxin type A injections were associated with improved hair growth and scalp condition in a patient with radiation-induced alopecia, though the mechanisms remain speculative.
9 citations
,
October 2014 in “Clinical and Experimental Dermatology” Temporary hair loss can occur after brain AVM treatment but usually regrows in 8 weeks.
4 citations
,
January 2016 in “Case reports in dermatological medicine” This case report describes a novel dermoscopic finding of blue-grey dots in a target pattern around yellow dots and follicles in radiation-induced alopecia following cerebral angiography with fluoroscopy.
July 2026 in “Open Science Framework” This review identifies higher radiation doses and larger scalp exposure as major factors in radiation-induced alopecia, highlights prevention techniques like IMRT and proton therapy, and discusses management options such as minoxidil and hair transplantation, but notes limited evidence for these treatments.
February 2026 in “Clinical Cosmetic and Investigational Dermatology” This case report describes a 7-year-old girl who developed radiation-induced alopecia after a neurointerventional procedure, with dermoscopy revealing specific hair and scalp patterns that helped diagnose this rare complication. The findings highlight the importance of dermoscopy in distinguishing RIA from other alopecic disorders in children.
November 2025 in “Journal of Investigative Dermatology” Radiation-induced hair loss may be caused by hair growth stopping and inflammation in blood vessels.
January 2023 in “Skin appendage disorders” This case report describes a patient who experienced proton-induced alopecia after proton therapy for a frontal meningioma, which was effectively treated with topical minoxidil, resulting in full hair regrowth after 4 months.
May 2019 in “Journal of clinical oncology” This study found that concurrent chemotherapy with radiotherapy may increase the risk of grade 2 persistent radiation-induced alopecia, while topical minoxidil showed potential benefits, though more research is needed on its efficacy.
6 citations
,
October 2007 in “Medical Hypotheses” This article proposes that androgenic alopecia might be an evolutionary mechanism for reducing prostate cancer risk by enhancing UV absorption, rather than being a risk factor.
4 citations
,
July 2005 in “International Journal of Dermatology” This article does not contain an abstract and presents no new clinical findings, instead discussing prior cases and literature on infant alopecia universalis and the potential role of topical PUVA therapy.
26 citations
,
August 2018 in “American Journal of Clinical Dermatology” This review discusses the clinical characteristics of alopecia in cancer patients, highlighting its potential role as an associated finding or diagnostic clue, but reports no new clinical results.
13 citations
,
May 2020 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This systematic review found inconclusive evidence on the effectiveness of botulinum toxin for treating alopecia and highlighted the need for further prospective randomized controlled trials.
June 2025 in “Clinical Cosmetic and Investigational Dermatology” This report presents a case where a 17-year-old male developed severe unilateral alopecia following radiotherapy for pediatric glioblastoma multiforme, which did not respond to minoxidil or platelet-rich plasma treatments.
13 citations
,
July 2004 in “Skinmed” This article reviews the structure and function of hair follicles, diagnostic approaches, and treatments for nonscarring alopecias, but reports no new clinical results.
5 citations
,
July 2022 in “Radiation Research” This study developed a mouse model to simulate chronic radiation-induced salivary dysfunction, revealing dose-dependent saliva reduction and glandular changes, which may help advance salivary regenerative therapies.
3 citations
,
December 2011 in “Pediatric Dermatology” In this case report, estrogen substitution therapy slightly increased hair volume in a 22-year-old patient with genetic predisposition to hair loss and alopecia caused by past treatment for leukemia, but hair loss returned after stopping the therapy.
1 citations
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November 2024 in “Journal of Cutaneous Pathology” This case study reported on a 72-year-old woman initially diagnosed with inflammatory alopecia, later identified as having angiosarcoma of the scalp, revealing the importance of considering unexpected malignancies during evaluation of suspected inflammatory alopecia cases.
March 2014 in “Journal of The American Academy of Dermatology” A botanical extract may help manage hair loss from chemotherapy by preventing cell death in hair follicles.
January 2022 in “Clinical Cases in Dermatology” This case report details a 26-year-old woman with diffuse hair loss following treatment for thyroid cancer, subsequent thyroidectomy, and development of hypothyroidism and hypoparathyroidism managed with thyroxin.
1 citations
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July 2022 in “Dermatology practical & conceptual” Square-shaped hair loss can occur after treating a brain aneurysm due to localized radiation exposure.
14 citations
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November 2005 in “Life sciences” This study indicates that vitamin D3 administration may protect rat hair follicles from radiation-induced damage, as evidenced by maintained follicle numbers and increased Vitamin D receptor activity in treated skin.