34 citations,
February 1993 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
32 citations,
January 1986 in “The Journal of Dermatologic Surgery and Oncology” Surgical correction can treat hair loss in black women caused by styling practices, with techniques chosen based on individual needs and hair loss severity.
9 citations,
March 2022 in “Journal of radiation research” Boron neutron capture therapy for head and neck cancer can cause side effects like mouth sores and skin irritation, which vary depending on where the treatment is aimed.
8 citations,
April 1965 in “Archives of biochemistry and biophysics” Sheep wool follicles can metabolize both glucose and acetate using different pathways important for wool growth.
1 citations,
October 2018 in “International Journal of Research in Dermatology” Most women with excessive hair growth in South India have hirsutism without a known cause, with common facial hair growth and some showing hormonal imbalances and polycystic ovaries.
1 citations,
December 1972 in “Journal of Colloid and Interface Science” Ethanol spreads well on hair at low humidity but less so at higher humidity due to water condensation.
1 citations,
April 1953 in “Acta Radiologica” Irradiating the whole central nervous system can lead to over 50% of patients with cerebellar medulloblastoma surviving three years.
November 2023 in “Benha Journal of Applied Sciences” Males with male pattern baldness have higher blood galectin-3 levels.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The mesenchyme can start hair growth, but the exact signal that causes this is still unknown.
April 2023 in “Journal of Investigative Dermatology” SOX2 helps reduce wound size and pressure ulcer formation by suppressing oxidative stress and increasing antioxidant activity in mice.
April 2023 in “Journal of Investigative Dermatology” Transplanted stem cells from hair follicles significantly boosted hair growth and normalized follicles in certain mice.
April 2023 in “Journal of Investigative Dermatology” An elderly woman's upper lip lump, thought to be a mucocele, was actually a rare type of lymphoma usually found on legs, treated successfully with chemotherapy and radiation.
July 2016 in “Experimental Dermatology” New treatments for hair growth and psoriasis may be possible, and gene differences could affect baldness and the severity of skin conditions.
The study concluded that hirsutism is most common in women aged 14 to 48, often caused by PCOS, and can be effectively treated with Nd YAG laser and IPL.
January 2016 in “Hematology & Transfusion International Journal” Platelet Rich Plasma (PRP) injections can improve hair count, thickness, and strength in people with androgenic alopecia.
218 citations,
December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
165 citations,
December 2002 in “Molecular and Cellular Endocrinology” Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
155 citations,
December 2002 in “Journal of Investigative Dermatology” Thyroid-related genes are active in skin cells and may affect autoimmune conditions.
115 citations,
March 2001 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Key enzymes control androgen levels, affecting hormone activity and potential treatments.
111 citations,
May 2001 in “Human reproduction update” Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.
97 citations,
January 1999 in “International Journal of Dermatology” Pityriasis rubra pilaris is a rare skin disorder with reddish-orange patches and thickened skin, needing better treatment understanding.
71 citations,
May 2007 in “The FASEB journal” Human hair follicles produce and respond to erythropoietin, helping protect against stress.
66 citations,
October 1999 in “Annals of the New York Academy of Sciences” The Skin POMC System affects hair growth and skin responses to stress.
51 citations,
May 2011 in “Phytotherapy Research” Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.
37 citations,
September 2018 in “Psychoneuroendocrinology” Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.
29 citations,
September 1997 in “PubMed” Follicular transplantation can greatly improve hair restoration if done with detailed planning and patient evaluation.
22 citations,
September 2018 in “Medical Clinics of North America” Facial aging is caused by natural processes and external factors, and can be managed with preventative measures and a variety of treatments tailored to individual needs.
22 citations,
March 2000 in “Clinics in Dermatology” Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
21 citations,
November 2017 in “Archives of Dermatological Research” Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.
20 citations,
February 2002 in “Expert Opinion on Therapeutic Patents” New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.