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PPAR agonists show promise for skin conditions but need more research before being a main treatment.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

Most hospitalized COVID-19 patients had long-term symptoms like fatigue and hair loss, with women and those sicker during hospitalization at higher risk.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.

Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.

Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.

Some medications can cause hair loss, but stopping the drug usually leads to recovery within 3 months.

FOXN1 gene variants cause low T cells and immune issues from birth.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Minoxidil can cause heart muscle damage in dogs.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Insulin resistance linked to obesity may increase COVID-19 severity.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.

Nude mice with grafted human skin developed scars similar to human hypertrophic scars.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.