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High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

Hormonal treatments can improve acne, but they come with potential side effects and risks.

Hormonal imbalances, often indicating conditions like PCOS, are common in women with hard-to-treat acne, and a treatment approach addressing these imbalances may be needed.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.

A patient with Satoyoshi syndrome improved with a treatment combining several medications, including carbamazepine and methotrexate.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

Finasteride doesn't affect erections much, but may decrease libido in men.

Sex hormones, especially estradiol, can change chicken feather shapes and colors.

The oral contraceptive ethinylestradiol/chlormadinone acetate is effective in reducing acne and improving other skin conditions related to high androgen levels.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

The document explains that hirsutism, often caused by hormonal issues, can be managed with treatment to improve both physical appearance and mental health.