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research 12-O-Tetradecanoylphorbol-13-acetate Induces Apoptosis in Renal Epithelial Cells through a Growth Signal Conflict Which Is Prevented by Activated ras1
This study found that TPA induces apoptosis in pig renal epithelial cells by affecting cell cycle proteins, and activated ras can prevent this process.
research Pretibial Pruritic Papular Dermatitis: A Case Report and Emphasis on Effective Treatment with Pentoxifylline
This report describes a 60-year-old female with pretibial pruritic papular dermatitis who showed significant improvement of skin lesions after one month of treatment with oral pentoxifylline. The authors highlight the unique clinical and histological features of PPPD and propose pentoxifylline as a potential therapy.
research Development and validation of PICAT - PRP injectable competency assessment tool for androgenic alopecia for dermatology residents
This study concluded that the platelet rich plasma injectable competency assessment tool (PICAT) demonstrated strong validity, internal consistency, and inter-rater reliability for evaluating dermatology residents at PNS Shifa Hospital.
research 13B “Temporary” Scalp Micropigmentation (Trichopigmentation)
This article discusses the temporary scalp trichopigmentation procedure, detailing its unique approach compared to traditional scalp micropigmentation, and reports no new clinical findings.
research 42736 Safety Assessments in the Multinational Phase 3 THRIVE-AA1 Trial with CTP-543 (Deuruxolitinib) in Adult Patients with Moderate to Severe Alopecia Areata
CTP-543 is generally safe for treating alopecia areata.
research Partial Penile Amputation due to Penile Tourniquet Syndrome in a Child Troubled With Primary Nocturnal Enuresis - A Rare Emergency
This case report describes an 8-year-old child with penile tourniquet syndrome due to a constricting thread, which led to partial distal penile amputation and required surgical intervention.
research Effects of adenosine triphosphate on vandetanib induced skin damage in rats
This study demonstrated that adenosine triphosphate may prevent vandetanib-induced skin toxicity in rats, suggesting potential for further research in other animal models and humans.
research Effects of prasugrel versus clopidogrel on coronary microvascular function in patients undergoing elective percutaneous coronary intervention: A randomized double-blind study
Prasugrel is better than clopidogrel at preventing heart damage and improving blood flow in small heart vessels during heart artery procedures.
research Case 4-2012
Early diagnosis and treatment of TPP can prevent complications.
research A Phase 3, Open-Label, Single-Arm Trial of the Efficacy and Safety of Triptorelin 6-Month Formulation in Chinese Children with Central Precocious Puberty
In this study, Chinese children with central precocious puberty receiving 6-monthly injections of triptorelin showed luteinizing hormone suppression and slowed development of sexual characteristics over 12 months, without severe adverse events, suggesting it may be an effective treatment option for this population.
research PD59-09 PHOSPHODIESTERASE INHIBITORS COULD REVERSE THE PROLIFERATION OF BPH EPITHELIAL CELLS INDUCED BY CD8+ T CELLS IN LOW ANDROGEN CONDITION
This study found that phosphodiesterase inhibitors may suppress the proliferation of benign prostatic hyperplasia epithelial cells by modulating CCL5 levels in low androgen conditions.
research Reply to: Platelet‐rich plasma application by dermapen microneedling and intradermal point‐by‐point injection methods, and their comparison with clinical findings and Trichoscan in patients with androgenetic alopecia
This article is a correspondence that discusses platelet-rich plasma application methods for androgenic alopecia but reports no new clinical results.
research Finasteride as a Neo-Adjuvant Treatment for TURPLiterature Review
This review discusses the role of finasteride preoperatively in reducing bleeding and complications during TURP and reports no new clinical results; the authors emphasize its potential benefits based on existing studies.
research Platelet-Rich Plasma for the Treatment of Tissue Infection: Preparation and Clinical Evaluation
This review discusses the antibacterial properties of platelet-rich plasma (PRP) and summarizes existing preclinical and clinical research on its use for preventing and treating wound and bone infections, but presents no novel data.
research 527 PTEN is a master driver of healing inhibition in venous leg ulcers by targeting immune response, angiogenesis and lymphangiogenesis
This study identified PTEN as a key regulator in non-healing venous leg ulcers, suppressing immune responses and lymphangiogenesis, suggesting its potential as a therapeutic target for promoting VLU healing.
research Diagnosis and treatment of prostatitis after TURP
This study concluded that intraprostatic injection with drugs and high frequency thermotherapy was more effective for treating prostatitis after TURP than a combination of antibiotherapy, tamsulosin, and finasteride.
research 1492 Prostacyclin pathway to enhance wound healing in diabetic foot ulcers
This study found that treprostinil, a prostacyclin analog, significantly delayed fibroblast migration from healthy donors but did not affect fibroblast migration derived from diabetic foot ulcers.
research Kombinationsbehandlung des BPS mit Tamsulosin und Finasterid
research PREVALENCIA DE APEGO AL TRATAMIENTO CON FINASTERIDA EN PACIENTES CON HIPERPLASIA BENIGNA DE PRÓSTATA DE UN SERVICIO DE UROLOGÍA DEL I.S.S.S.T.E.
This study observed that adherence to finasteride treatment in patients with benign prostatic hyperplasia at a clinic in Tepic Nayarit had not been previously evaluated in Mexico.
research Increased risk of telogen effluvium with tirzepatide compared to other weight-loss medications: a retrospective cohort TriNetX database study
research A Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Assess the Efficacy of a Nutritional Supplement in Female Androgenic Alopecia
In this randomized controlled trial, the nutritional supplement PPT5 α was associated with increased terminal hair percentages and improved self-assessed hair parameters in women with early-stage androgenetic alopecia.
research Parenteral Nutrition Trace Element Product Shortage Considerations
This article provides guidelines by ASPEN for managing parenteral nutrition shortages but reports no new clinical findings.
research [Prophylaxis of recurring low-flow priapism : Experimental botulinum neurotoxin injection into the ischiocavernosus muscle].
In this case report, botulinum neurotoxin injections were associated with a 6-month cessation of priapism episodes in a young man with recurring low-flow priapism, following unsuccessful conventional treatments.
research Safety and efficacy of advanced and targeted acid α-glucosidase (AT-GAA) (ATB200/AT2221) in ERT-switch nonambulatory patients with Pompe disease: preliminary results from the ATB200-02 trial
This study found that coadministration of tadalafil and finasteride improved lower urinary tract symptoms and erectile function in men with benign prostatic hyperplasia better than finasteride alone over 26 weeks.
research P4 Outcome following switch between brand name and generic tacrolimus in paediatric population
In this study, researchers at Nottingham Children's Renal Unit found that most pediatric patients switching from Prograf to the generic tacrolimus preparation Adoport maintained stable tacrolimus levels and therapeutic effectiveness, supporting Adoport's use as a cost-saving alternative for the NHS.
research MP74-11 TRENDS IN THE PHARMACOTHERAPY OF NOCTURIA, 2016-2021: ANALYSIS OF A LARGE MULTI-INSTITUTIONAL RESEARCH NETWORK
This study observed that despite the increase in nocturia cases from 2016 to 2021, the use of pharmacotherapy for the condition declined, suggesting potential undertreatment.
research Finasteride to treat recurrent priapism in sickle cell anemia
research Key Clinical Trials in BPH
This review discusses various treatments for benign prostatic hyperplasia, comparing medications like finasteride and terazosin, as well as surgical and placebo options, without presenting new clinical findings.