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The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Growing human skin cells in a 3D environment can stimulate new hair growth.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

Dermatoscopy is useful for identifying different hair and scalp conditions and can reduce the need for biopsies.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

FPHL affects hair density and diameter, causing visible hair loss in older women.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Nerves are crucial for the regeneration of various body parts in many animals.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.