research Androgen Receptor Mutations and Polymorphisms in African American Prostate Cancer
African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.
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450-480 / 1000+ results research Ezetimibe Reduces Enlarged Prostate in an Animal Model of Benign Prostatic Hyperplasia
Ezetimibe effectively reduces prostate size in cases of benign prostatic hyperplasia.
research Impact of Medical Castration on Malignant Arrhythmias in Patients With Prostate Cancer
Medical castration in prostate cancer patients can increase the risk of serious heart rhythm problems, so it's important to monitor heart activity during treatment.
research Effect of the Dual 5α-Reductase Inhibitor Dutasteride on Markers of Tumor Regression in Prostate Cancer
Dutasteride may help shrink prostate cancer tumors.
research Change in Prostate-Specific Antigen Concentration in Men with Prostate-Specific Antigen Less Than 2.5 ng/mL Taking Low-Dose Finasteride or Dutasteride for Male Androgenetic Alopecia
Low-dose finasteride and dutasteride reduce PSA levels by 27.8% in men with male androgenetic alopecia.
research Risk Factors for Prostate Cancer: An Umbrella Review of Prospective Observational Studies and Mendelian Randomization Analyses
Physical activity, height, and smoking affect prostate cancer risk.
research Finasteride and Prostate Cancer
Finasteride's effects on prostate cancer are not clear from this text.
research Management of Advanced Prostate Cancer Undergoing Major Shift
New treatments are making advanced prostate cancer management more complex but also more hopeful.
research Detection of Circulating Prostate Cancer Cells by Means of an Antibody-Conjugated Nanoparticulate Biosensor
The document concludes that a new biosensor can efficiently detect prostate cancer cells and that standardized referrals help find significant cancers effectively.
research Urological Oncology: Prostate Cancer
Male pattern baldness may be linked to prostate cancer risk.
research Slow Progress in Prostate Cancer
Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.
research How Not to Detect Prostate Cancer
Using a single PSA level to decide on a prostate biopsy is not effective; a more personalized approach considering various factors is recommended.
research TRAIL Sensitization of PC3 Prostate Cancer Cells by Doxorubicin Can Be Blocked by the Antioxidant N-Acetyl-Cysteine or by the Iron Chelator Deferoxamine
Antioxidants can block the cancer-fighting effects of doxorubicin.
research Effect of the Dual 5α-Reductase Inhibitor Dutasteride on Markers of Tumor Regression in Prostate Cancer
Dutasteride may help treat prostate cancer by causing cancer cells to shrink and die.
research Can We Predict Prostate Size by Scoring Baldness? The Relationship of Androgenic Alopecia and Lower Urinary Tract Symptoms
research Incidence of Liver Toxicity Associated with the Use of Flutamide in Prostate Cancer Patients
Flutamide rarely causes liver toxicity in prostate cancer patients.
research The Rationale for Inhibiting 5α-Reductase Isoenzymes in the Prevention and Treatment of Prostate Cancer
Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.
research Prospective Investigation of Risk Factors for Prostate Cancer in the UK Biobank Cohort Study
Black ethnicity, prior PSA tests, enlarged prostate, and family history increase prostate cancer risk; Asian ethnicity, obesity, smoking, diabetes, and less sexual activity or no children decrease risk.
research Five-Alpha-Reductase Inhibitors for Prostate Cancer Prevention
5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.
research Androgenetic Alopecia and Risk of Prostate Cancer: A Systematic Review and Meta-Analysis
Vertex pattern hair loss linked to higher prostate cancer risk.
research Post-Screening Follow-Up of the Finnish Prostate Cancer Screening Trial on Putative Prostate Cancer Risk Factors: Vitamin and Mineral Use, Male Pattern Baldness, Pubertal Development, and Non-Steroidal Anti-Inflammatory Drug Use
Late puberty may slightly lower prostate cancer risk, baldness is not linked to overall risk but less so with aggressive types, ibuprofen use may increase risk, and vitamins show no effect on risk.
research Clinical and Metabolic Implications of Obesity in Prostate Cancer: Is Testosterone a Missing Link?
Higher BMI and lower testosterone are linked to more aggressive prostate cancer.
research The Investigation of Minoxidil-Induced Ca2+ Rises and Non-Ca2+-Triggered Cell Death in PC3 Human Prostate Cancer Cells
Minoxidil increases calcium levels and kills prostate cancer cells independently of calcium.
research Anti-Proliferative Effect of Terpenes on Human Prostate Cancer Cells: Natural Sources and Their Potential Role as Chemopreventive Agents
Certain natural compounds called terpenes may help prevent prostate cancer.
research Long-Term Consequences of Finasteride vs Placebo in the Prostate Cancer Prevention Trial
Finasteride reduces the need for prostate surgery but may increase the risk of depression and persistent sexual side effects.
research A Powerful Method for Pleiotropic Analysis Under Composite Null Hypothesis Identifies Novel Shared Loci Between Type 2 Diabetes and Prostate Cancer
New method finds genetic links between Type 2 Diabetes and Prostate Cancer not seen before.
research Comparison of Saw Palmetto (Extract and Whole Berry) and Cernitin on Prostate Growth in Rats
research Effects of Short-Term Finasteride on Apoptotic Factors and Androgen Receptors in Prostate Cancer Cells
Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.
research Multiple Readout Assay for Hormonal (Androgenic and Antiandrogenic) and Cytotoxic Activity of Plant and Fungal Extracts Based on Differential Prostate Cancer Cell Line Behavior
The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
research Evaluation of RU58841 as an Anti-Androgen in Prostate PC3 Cells and a Topical Anti-Alopecia Agent in the Bald Scalp of Stumptailed Macaques
RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.