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Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Androgens can both increase and decrease hair growth in different parts of the body.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Lactate production is important for activating hair growth stem cells.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

The cuneate nucleus has two main neuron types: relay neurons and interneurons.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

Dermoscopy helps diagnose and manage alopecia areata by showing specific hair changes.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Targeted cancer therapies often cause serious skin problems that need careful management.

Hair loss can cause low self-esteem, anxiety, and depression in men.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Sulforaphane from broccoli can help protect skin from sun damage.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Fluoxetine was not effective in treating hair-pulling disorder in the short term.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.