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In this study, researchers identified PSENEN mutations that can lead to a form of Dowling-Degos disease, characterized by follicular hyperkeratosis and an increased susceptibility to acne inversa, especially in the presence of certain trigger factors.

This study found that emodin from Polygonum multiflorum showed 5alpha-reductase inhibitory activity, which was more potent than alizarin but less potent than riboflavin.

Finasteride and dutasteride may increase the risk of depression and suicidality, so patients should be monitored closely.

In this study, finasteride was found to potentiate stress-induced disruption in sensory gating of rats by neutralizing the increase in allopregnanolone levels after acute stress.

This case report describes a 4-year-old girl with hypotrichosis and juvenile macular dystrophy, linked to mutations in the cadherin 3 gene affecting P-cadherin expression.

In this case report, an 18-year-old Vietnamese female with primary amenorrhea and normal female phenotype was most likely diagnosed with müllerian agenesis, highlighting its association with embryologic underdevelopment of the müllerian duct.

This article discusses the late presentation of myotonic dystrophy but reports no new clinical findings.

This study introduces genital sex differentiation parameters (GSDP) to analyze sexual differences in external genitalia and perineum development in mice, revealing varied sensitivity to androgen inhibition in genital structures.

This study found a significant association between AGDAC measurements and the presence of PCOS, suggesting it could be an effective clinical tool in diagnosing the condition and its phenotypes, especially when combined with AMH.

This case report describes a woman experiencing severe hair loss due to allergic contact dermatitis from a hair dye containing PPD.

Some people have a genetic variation that makes them less effective at breaking down drugs.

This study developed a new clustering model to improve detection of drug-induced cognitive disorder risk signals, finding that it identified drugs with moderate risk signals, like Carbidopa/Levodopa, missed by traditional methods, enhancing clinical assessment comprehensiveness.

Finasteride caused blisters on hands and feet.

This case study identified erosive pustular dermatosis of the scalp following methylaminolaevulinate photodynamic therapy, noting improvement with steroid treatment and partial resolution of atrophy after three months.

This article reviews adolescent sexual behavior and emphasizes the importance of hormonal contraception for sexually active teenagers, suggesting that health care providers play a crucial role in addressing their reproductive needs.

This study found that melatonin-loaded nanoparticles improved antidepressant effects and HPA axis regulation in pinealectomized rats, compared to free melatonin, through controlled-release properties.

This study presents the first reported Spanish case of Hypotrichosis with Juvenile Macular Dystrophy, identifying a new CDH3 mutation and highlighting the importance of clinical and genetic evaluation for accurate diagnosis.

Body dysmorphia is common in women with PCOS, affecting their quality of life.

Bullous pemphigoid can look like erythema multiforme, so awareness is needed for proper treatment.

This review discusses the classification and treatment of ejaculatory dysfunction, outlining both pharmacotherapy and behavioral therapy as primary interventions, but does not present new clinical findings.

This study found that Mdm2 is critical for limiting p53 activity to maintain normal stem cell function in mouse skin, with impacts on tissue homeostasis and aging.

This review discusses psychocutaneous disorders in children with an emphasis on primary psychiatric disorders manifesting through skin symptoms, but provides no new clinical findings.

Medroxyprogesterone acetate improved sleep apnea symptoms in some obese patients.

This study investigated premature greying and found lower levels of vitamin D and vitamin B12 in affected individuals compared to controls, associating micronutrient deficiencies with altered hair pigmentation, though no significant link between micronutrient deficiencies and inflammatory markers was observed.

This case report details an unusual instance of multiple eruptive milia in an otherwise healthy 3-month-old baby, characterized by widespread distribution and believed to be idiopathic due to the absence of associated genodermatoses.

This review discusses the occurrence of persistent sexual, physical, neurological, and psychiatric side effects known as post-finasteride syndrome after 5x-reductase inhibitor treatment, and emphasizes the importance of evaluating these risks for patients with benign prostatic hyperplasia or androgenic alopecia.

This study revealed significant signals of drug-related cognitive disorders in several medications that lack relevant FDA label warnings, suggesting a need for increased clinical awareness and potential label updates.

Finasteride may help improve certain brain function issues linked to dopamine.

This study found that 29.6% of patients seeking treatment for hair loss meet the criteria for hair-related body dysmorphic disorder, significantly higher than in general dermatology patients.