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In this review, researchers explored thermo-responsive polymers and their applications in nanomedicine, highlighting their role in targeted drug delivery, gene therapy, and imaging, enabled by their temperature-sensitive phase transitions to ensure localized therapeutic action and minimize damage to healthy tissues.

In this review, the authors emphasize that phenotypic heterogeneity in genetic systems and human diseases is influenced by stochastic fluctuation and network topology, proposing that ultrasensitivity and threshold effects explain this variability, which may inform strategies for preventing and treating genetic diseases.

This study found that modulating BMP activity in transgenic mice affects the development and characteristics of several ectodermal organs, such as skin, hair, and claws, highlighting a stage-dependent influence on organogenesis.

This study observed a high degree of plasticity in somatosensory axons innervating Merkel cells in mouse skin, finding that both axons and Merkel cells underwent dynamic remodeling, with their interactions influencing axonal branching and maturation.

This study developed granular hydrogels with reversible interparticle cross-linking, finding they offer high mechanical stability and enhance cell recruitment, making them promising for injectable and 3D printable scaffolds in tissue engineering and therapeutic delivery.

CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.

This study found that in wound-induced hair neogenesis, African spiny mice and laboratory mice exhibit different morphogenetic field formation patterns related to tissue stiffness, suggesting evolutionary developmental biology advantages.

This study found that knocking out vinculin in mouse skin disrupts bulge stem cell quiescence by impairing force generation and mechanical stability of adherens junctions.

This study used confocal Brillouin microscopy to observe that a decrease in tissue compressibility occurs during the development and regeneration of axolotl limbs, suggesting mechanical changes linked to regeneration stages undetectable by fluorescence microscopy.

This study experimentally validated Lockhart's viscoplastic framework for tip growth in Arabidopsis root hairs by demonstrating alignment with observed growth rates and estimating yield turgor pressure and cell wall viscosity, offering a methodology adaptable to other species and conditions.

This study validated a new tool for assessing curly hair manageability, finding that hair curvature is a key factor influencing hair practices and product attitudes among women with natural curly hair.

This study found that transcriptional regulation by Runx1 and cyclin-dependent kinase inhibitors plays a crucial role in maintaining quiescence and promoting fate decision flexibility in hair follicle stem cells.

This study found that straight crimp mutant wool differs from crimpy wool in the layout of cortical cells and the relative proportions of keratin and keratin-associated proteins.

In this study, fibroblasts from long-term skin biopsy cultures retained their ability to reprogram into induced pluripotent stem cells after 16 months, despite undergoing transcriptional changes and decreased proliferation rates over successive generations.

This paper examines factors affecting the stretching setting treatment of human hair and wool, concluding that the intended outcomes can be achieved using their customized testing equipment and technology.

This study found that greater root surface area due to root hairs contributed to better growth and zinc uptake of wild-type barley compared to its root-hairless mutant in zinc-deficient soil.

This study found that mouse embryoid bodies adhered quickly and differentiated efficiently into cardiomyocytes on negatively charged poly(sodium p-styrene sulfonate) hydrogels, similar to their behavior on gelatin-coated polystyrene.

This study found that the cuticle layer of hair contributes approximately 60% to bending stress, highlighting its significant role in the mechanical properties of hair stiffness.

This article explores the evolution of mechanosensing and discusses the diverse forms and organization of touch receptors but reports no new research findings.

This study investigated various animal tissues from adult mice and embryonic chicks, finding that tissue stiffness follows a sub-linear power law relationship with Collagen-I levels, consistent with cellularized collagen gels but not acellular ones.

This review highlights the potential of spanlastics, a new type of drug delivery system, to enhance drug administration by offering better deformability and stability compared to other nanocarriers, potentially improving targeted drug delivery across various applications.

This study introduced a theoretical model suggesting that the morphological transition from bud to cap in tooth germ development is driven by mechanical interactions among cells.

This study found that chemically modifying human hair through esterification or disulfide reduction and alkylation affects the hair's viscoelastic properties, including stability, integrity, and response to moisture.

Mechanical stretching can improve or hinder skin regeneration depending on duration.

Adding keratin to a mix of cow hair and plant-based plastic makes it stronger.

This study developed a 3D computational model to simulate how skin, fat, and muscle deform under suction, reporting that as suction pressure increased, skin thickness decreased, while fat thickness increased, and muscle thickness remained stable, closely aligning with experimental results.

In this study, researchers observed a high degree of plasticity in somatosensory axons innervating Merkel cells in adult mouse skin, with both epithelial and neural components exhibiting dynamic remodeling, highlighting intricate epithelial-neural interactions in maintaining homeostasis.