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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Skin problems are very common in people with end-stage kidney disease.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Women with AGA often face anxiety, depression, and low self-esteem; psychological support is important.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Finasteride helps reduce priapism in sickle cell anemia patients.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Finasteride for hair loss has minimal impact on sexual function.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Hormone therapy and surgeries for transgender individuals affect their skin and hair, requiring specific dermatologic treatments and respectful care.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.