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Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Special fiber materials boost the healing properties of certain stem cells.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Targeting the skin's endocannabinoid system could help treat skin disorders.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.