May 2024 in “International journal of medicine and psychology.” This article describes an increase in the detection of heart failure among young people and discusses the development of the drug Uperio for its treatment and support.
This study on alopecia areata meta-analyses highlights the risk of misleading results when ineffective, unsafe, or unapproved dosing regimens are included, recommending methodological safeguards to ensure accurate data interpretation and avoid inappropriate causal inferences.
January 2020 in “the british journal of cardiology” This case report suggests that the progestogen-only pill may cause false-positive aldosterone/renin ratio results in primary hyperaldosteronism screening, indicating it should be omitted before testing.
November 2013 in “Hair transplant forum international” This article discusses the author's experience with prescribing generic finasteride for hair restoration but reports no new clinical findings.
November 2022 in “Journal of the Endocrine Society” This case study suggests that long-term treatment with buprenorphine/naloxone for opioid addiction may lead to secondary adrenal insufficiency, warranting further investigation.
August 2012 in “Pharmaceutical Medicine” The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.
September 2023 in “Dermatology Online Journal” A newspaper article caused a big rise in oral minoxidil prescriptions for hair loss.
2 citations
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November 2004 in “Hospital pharmacy” This article reviews adverse drug reactions, emphasizes methods of prevention, and encourages reporting to the FDA's medWatch program, but presents no new study findings.
1 citations
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October 2012 in “Medical Hypotheses” The conclusion suggests that treatments targeting root causes of chronic diseases may be developed by focusing on gene expression and lifestyle factors.
246 citations
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February 2021 in “Trends in Pharmacological Sciences” This review discusses drug repurposing strategies for rare diseases, highlighting methodologies, achievements, and challenges, but reports no new clinical results.
25 citations
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January 1978 in “JAMA” This case report describes a 45-year-old woman who developed Cushing's syndrome and hirsutism after using topically applied desoximetasone (Topicorte).
This study detected insomnia risk signals associated with various medications, primarily nervous system drugs, using the FDA's Adverse Event Reporting System data from 2004 to 2024.
June 2025 in “The Senior Care Pharmacist” This study observed that certain medications, including antipsychotics, non-sedating antidepressants, and finasteride, were associated with a higher risk of inpatient falls among older adults at a Veterans Affairs Medical Center compared to matched controls.
Media coverage led to more dermatologists prescribing low-dose oral minoxidil for hair loss.
3 citations
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July 2025 in “BIOMED natural and applied science” This systematic review synthesizes the current state of drug repurposing, revealing its potential in various therapeutic areas like oncology and infectious diseases through insights from mechanistic studies and real-world evidence, and discusses emerging tools and challenges in the field.
April 2019 in “The Journal of urology/The journal of urology” After the FDA's 2011 warning about a potential prostate cancer risk with 5-alpha reductase inhibitors, this study observed a significant decrease in their prescriptions, notably a 49% drop among men with benign prostatic hyperplasia, while primary care providers reduced prescriptions by 60%.
January 2026 in “Nutrición Hospitalaria” In this study, researchers identified significant signals indicating previously unrecognized risks of lipid metabolism abnormalities for several drugs, urging the need for better monitoring and label updates.
3 citations
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January 2010 in “Actas Dermo-Sifiliográficas” This paper reviews the growing use of psychotropic drugs in dermatology due to the link between mental states and skin conditions but does not present new clinical findings.
5 citations
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July 2008 in “The Journal of Urology” This editorial examines the use of multiple drugs for treating lower urinary tract symptoms due to benign prostatic hyperplasia but offers no new research findings.
January 2016 in “Reactions Weekly” A girl's hair loss from a pharmacy error improved after getting the right medicine.
September 2025 in “Archives of Dermatological Research” February 2019 in “Urology” This study observed that the out-of-pocket prices for generic medications used to treat benign prostatic hyperplasia can vary by up to 500% among pharmacies in the Pittsburgh area, with chain pharmacies pricing significantly higher than independents.
May 2026 in “The Bioscan.” This review discusses the process and advantages of drug repurposing, highlighting its potential to expedite development and improve therapeutic outcomes with examples like sildenafil and metformin.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This policy brief reports that post-drug syndromes like Post-Finasteride Syndrome are largely overlooked in current pharmacovigilance systems, which prioritize acute drug reactions, resulting in inadequate recognition and management of persistent medication-induced conditions.
1 citations
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November 2008 in “Gerontology” This article discusses the increasing use of lifestyle drugs by healthy individuals to alter appearance or slow aging and emphasizes the need for doctors to consider side effects and contraindications, but it reports no new clinical findings.
May 2023 in “JAMA network open” After a New York Times article talked about using low-dose oral minoxidil for hair loss, more people started getting this drug prescribed, but this trend didn't last long.
10 citations
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November 2019 in “American Journal of Tropical Medicine and Hygiene” This case report highlights a patient who developed pancytopenia, transaminase elevation, and alopecia after consuming large amounts of veterinary albendazole purchased online, which he used without medical supervision.
This review article discusses current trends and future perspectives in drug repurposing, highlighting its potential to discover novel treatments for unmet medical needs by identifying new uses for existing drugs, which benefits from faster development timelines and established safety profiles.
April 2026 in “C&EN Global Enterprise” This narrative account, reported by C&EN, describes how Houston's use of a hormone-related hair loss treatment may have triggered unexpected panic attacks, contributing to ongoing mental health challenges, and highlights broader issues with mental health disorders that resist traditional treatments.