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Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Some patients receiving pegylated interferon alfa injections developed skin necrosis, requiring treatment adjustments or discontinuation.

Blocking IL-12/IL-23 does not help with hair loss in alopecia areata for mice or humans.

The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.

Switching to extended-release divalproex sodium improved patient-reported tremor but did not change seizure frequency or most side effects.

Vitiligo patients should be routinely screened for thyroid disease and, if extensive or prolonged, also for RA, PA, and type 2 diabetes.

Levetiracetam may cause hair loss, which can potentially reverse with lower doses or stopping the drug.

Some tuberculosis drugs may cause hair loss, but hair might regrow after treatment or changing the drugs.

The best animal model for studying male-pattern baldness is the stumptailed macaque, not rats or mice.

Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.

Severe male balding may increase the risk of serious COVID-19, and treatments that reduce androgens or block a specific enzyme might help protect these individuals.

The Hairless gene is crucial for hair cell development, affecting whether skin cells become hair or skin and oil gland cells.

Hair restoration using micrografts and minigrafts can provide natural-looking hair without scars and good density in 1 or 2 sessions.

Low-dose oral minoxidil effectively treats mild-moderate male hair loss, alone or combined with other therapies.

Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.

Minoxidil in distearyldimethylammonium chloride vesicles significantly promotes hair growth, while minoxidil in microparticles or poloxamer solutions doesn't.

The conclusion is that different types of hair loss in dogs and cats can be cosmetic or serious, and affected animals should not be bred.

Many hospitalized children with COVID-19 had skin, mouth, or nail changes, with skin rashes being common.

The patient's hair loss was likely not caused by beta blockers but possibly by stress or other factors.

Up to half of people experience itchy scalp, often due to skin conditions like seborrheic dermatitis or psoriasis, and treatments vary based on the specific cause.

Alopecia in animals can be hereditary, congenital, or acquired, with treatments and outcomes varying widely.

Omega-3 fatty acids may not help and could harm hair loss improvement in middle-aged or elderly men.

Blocking DPP4 can potentially speed up hair growth and regeneration, especially after injury or in cases of hair loss.

Radiation treatment causes skin fibrosis by increasing certain fibroblast subpopulations, but using a c-Jun inhibitor or fat grafting can reduce this effect.

Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.

Elderly patients with CCCA were all African American with low vitamin D, but no iron or zinc deficiencies, and no hormonal imbalances compared to younger patients.

Acne keloidalis nuchae is a chronic skin condition more common in African men, causing itchy or painful bumps and can lead to permanent hair loss if not treated early.

Psoriasis patients are willing to pay less than the cost of biologic treatments for remission and don't expect complete or long-term symptom clearance.

The document concludes that the discussed biological mechanisms and potential therapies are not related to hair loss or hair growth.