research Skin Aging as a Mechanical Phenomenon: The Main Weak Links
Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.
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research How to Distinguish Medicalization from Over-Medicalization?
The article suggests using four questions to tell apart necessary medicalization from excessive medicalization, focusing on problem significance, social expectations, medical understanding, and effective resolution.
research Janus Kinase (JAK) Inhibitors for the Treatment of Skin and Hair Disorders: A Review of Literature
JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.
research CD4+CD25+FoxP3+ Regulatory Tregs Inhibit Fibrocyte Recruitment and Fibrosis via Suppression of FGF-9 Production in the TGF-β1 Exposed Murine Lung
Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.
research Desferrioxamine Treatment of Aceruloplasminemia: Long-Term Follow-Up
Finasteride may help reduce symptoms in male Tourette syndrome patients.
research Refinement of Technique in Injection Lipolysis Based on Scientific Studies and Clinical Evaluation
Injection lipolysis effectively reduces small fat deposits and should be done with care and proper patient selection.
research Body Composition Changes and Inhibition of Fat Development In Vivo Implicate Androgen in Regulation of Stem Cell Lineage Allocation
Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
research The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells
The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.
research Development of a Two-Dimensional Model for Predicting Transdermal Permeation with the Follicular Pathway: Demonstration with a Caffeine Study
Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.
research Inhibition of the Androgen Receptor by Antisense Oligonucleotides Regulates the Biological Activity of Androgens in SZ95 Sebocytes
Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.
research Polycystic Ovary Syndrome in Adolescence and Type 2 Diabetes
Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.
research A Review of Hedgehog Inhibitors Sonidegib and Vismodegib for Treatment of Advanced Basal Cell Carcinoma
Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.
research Combined Oral Contraception and Bicalutamide in Polycystic Ovary Syndrome and Severe Hirsutism: A Double-Blind Randomized Controlled Trial
Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.
research Aesthetic Facial Surgery for the Asian Male
The article concludes that surgeons should tailor facial surgery techniques for Asian males to their unique cultural and anatomical needs.
research A Review of Hand-Held, Home-Use Cosmetic Laser and Light Devices
Home-use cosmetic laser and light devices show modest results for hair removal and acne treatment, but more research is needed for confirmation.
research Injectable Platelet-Rich Fibrin: The Newest Biomaterial and Its Use in Various Dermatological Conditions in Our Practice: A Case Series
Injectable Platelet-Rich Fibrin (I-PRF) showed positive results for treating hair loss, skin texture, wrinkles, and wounds.
research Is Skin Microneedling a Good Alternative Method for Various Skin Defects Removal
Microneedling is a safe and effective way to improve various skin conditions with minimal side effects.
research Acquired Trichomegaly of the Eyelashes and Hypertrichosis Induced by Bimatoprost
Bimatoprost can cause longer, thicker, darker eyelashes and eyebrows.
research Negative Pressure Wound Therapy Augmented Full-Thickness Free Skin Grafting in Cats: Outcome in 10 Grafts Transferred to Six Cats
Negative pressure wound therapy is effective for skin grafts in cats.
research 5α-Reductase Inhibitors and Prostatic Disease
5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.
research Bladder Cancer Survival of Men Receiving 5α-Reductase Inhibitors
Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.
research Accelerated Senescence in Skin in a Murine Model of Radiation-Induced Multi-Organ Injury
High-dose radiation speeds up aging in skin stem cells.
research Endocrine and Reproductive Effects of Polycystic Ovarian Syndrome
Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.
research Pathological Findings in a Case of Stiff Person Syndrome with Anti-GAD Antibodies
Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.
research Interleukin-6 Null Mice Paradoxically Display Increased STAT3 Activity and Wound-Induced Hair Neogenesis
Mice without the IL-6 gene had more hair growth after injury due to higher activity of a related protein, Stat3.
research Teriflunomide: A Novel Oral Treatment for Relapsing Multiple Sclerosis
Teriflunomide is an effective and safe first-line oral treatment for relapsing multiple sclerosis.
research Antiandrogen Drugs Lower Serum Prostate-Specific Antigen Levels in Hirsute Subjects: Evidence That Serum PSA Is a Marker of Androgen Action in Women
Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.
research Short- and Long-Term Effects of Two Emollients on Itching and Skin Restoration in Xerotic Eczema
Both emollients effectively reduced itching and improved skin moisture in xerotic eczema.
research The Role of Therapy in Impairing Quality of Life in Dermatological Patients: A Multinational Study
Skin treatment can lower life quality for patients with skin conditions.
research What Ages Hair?
Hair aging and loss are caused by genetics, hormones, environment, and grooming, with treatments like minoxidil effective for certain types of hair loss.