Cutaneous Adverse Events of Tyrosine Kinase Inhibitors in Endocrine Tumors: Clinical Features, Mechanisms, and Management Strategies

    December 2025 in “ Biomedicines ”
    Marta Marino, Francois Rosset, Alice Nervo … Emanuela Arvat
    Studysummary This source reviews the common skin-related side effects of tyrosine kinase inhibitors in treating endocrine cancers and emphasizes that proactive, multidisciplinary management can effectively control these adverse events without compromising cancer treatment efficacy.
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    Research cited in this study 6

    1. Low-Dose Oral Minoxidil Initiation for Patients With Hair Loss JAMA Dermatology · 2024
    2. Topical Minoxidil and Dietary Supplement for the Treatment of Chemotherapy-Induced Alopecia in Childhood: A Retrospective Cohort Study Scientific Reports · 2024
    3. Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails American Journal of Clinical Dermatology · 2018
    4. Hair Disorders in Patients with Cancer Journal of The American Academy of Dermatology · 2018
    5. Cutaneous Reactions to Chemotherapeutic Drugs and Targeted Therapy for Cancer Journal of the American Academy of Dermatology · 2014
    6. Tyrosine Kinase Inhibitors: A Review on Pharmacology, Metabolism, and Side Effects Current drug metabolism · 2009