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    Glossary Estrogen Deficiency

    insufficient estrogen production affecting reproductive health and bone density

    Estrogen deficiency, also known as low estrogen, occurs when the body produces insufficient levels of estrogen, a key hormone in regulating the reproductive system and secondary sexual characteristics. This condition can lead to symptoms such as irregular menstrual cycles, hot flashes, mood swings, and can increase the risk of osteoporosis due to decreased bone density. It is commonly seen in postmenopausal women but can also affect younger women due to various medical conditions or treatments.

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    1. Anatomical and Dermatologic Manifestations of Estrogen Deficiency in Postmenopausal Women: A Systematic Review Pakistan Journal of Health Sciences · 2025
    2. MANAGING ESTROGEN-DEFICIENT SKIN: A NARRATIVE REVIEW ON THE ROLE OF HRT AND EMERGING ESTROGEN-MODULATING THERAPIES International Journal of Innovative Technologies in Social Science · 2025
    3. SAT-130 Estrogen deficiency in patients with reduced fat mass as a cause of non-alcoholic fatty liver disease Journal of the Endocrine Society · 2025
    4. PSAT217 Estrogen Deficiency as a Cause of Decreased 1- alpha - hydroxylase Activity Journal of the Endocrine Society · 2022
    5. The role of estrogen in cutaneous ageing and repair Maturitas · 2017 · 158 citations
    6. The effects of oestrogens on linear bone growth 2001 · 11 citations
    7. Aromatase deficiency in a male patient - Case report and review of the literature. Bone · 2016 · 36 citations
    8. Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells International Journal of Molecular Sciences · 2022 · 8 citations
    9. Collagen, Curcumin, and Glutathione to Enhance Dermal Health in Aging Women with Declining Estrogen Levels -A Narrative Review. PubMed · 2026
    10. Cutaneous manifestations of endocrine-metabolic disease and nutritional deficiency in the elderly Dermatologic Clinics · 2004 · 18 citations
    11. Disorders of sex development (DSD) 46.XY due to type 2 5-α reductase deficiency in three siblings: Case report from a low-resource setting Annals of medicine and surgery · 2022
    12. [Epididymis in an experimental model of DHT deficiency: immunolocalization of ERalpha and ERbeta in rat epididymal epithelial cells. In vivo and in vitro studies]. PubMed · 2006 · 4 citations
    13. Determinants of Plasma Androgen and Estrogen Levels in Men Data Archiving and Networked Services (DANS) · 2006
    14. Skin connective tissue and ageing Best Practice & Research in Clinical Obstetrics & Gynaecology · 2013 · 77 citations
    15. [Hormone replacement treatment and skin aging]. PubMed · 1996 · 16 citations
    16. Causes of hair loss and the developments in hair rejuvenation International Journal of Cosmetic Science · 2002 · 69 citations
    17. The therapeutic use of androgens in women The Journal of Steroid Biochemistry and Molecular Biology · 1999 · 51 citations
    18. The Hormonal Background of Hair Loss in Non-Scarring Alopecias Biomedicines · 2024
    19. Skin ageing Menopause International · 2007 · 76 citations
    20. Hormonale Diagnostik der sogenannten androgenetischen Alopezie der Frau Geburtshilfe und Frauenheilkunde · 1988 · 25 citations
    21. Testosterone Treatment in Women – An Overview Current Women's Health Reviews · 2009 · 8 citations
    22. Diffuser Haarausfall und klinische Endokrinologie: Neue Erkenntnisse Journal für Kardiologie (Krause & Pachernegg GmbH) · 2013
    23. Androgen Treatment in Women Postgraduate obstetrics & gynecology · 2007
    24. Estrogens and aging skin Dermato-endocrinology · 2013 · 150 citations
    25. Menopause and aging, quality of life and sexuality Climacteric · 2007 · 55 citations
    26. Young coconut juice can accelerate the healing process of cutaneous wounds BMC Complementary and Alternative Medicine · 2012 · 19 citations
    27. Metabolic Syndrome, Hepatic Steatosis and Testosterone: A Matter of Sex Livers · 2024 · 7 citations
    28. Human skin Menopause · 2016 · 6 citations
    29. Dermatological effects of menopausal hormone therapy: A path to overcoming hormone phobia Meditsinskiy sovet = Medical Council · 2026
    30. Mechanisms of testosterone action 2021