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    Glossary Nuclear Receptors

    proteins that regulate gene expression in response to hormones

    Nuclear receptors (NRs) are a class of proteins found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules. When these receptors bind to their specific ligands, they can directly influence the expression of specific genes, thereby regulating various biological processes such as metabolism, development, and cell differentiation.

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    Research 30 of 1000+

    1. The <i>hairless</i> gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor Genes & Development · 2001 · 178 citations
    2. The role of nuclear hormone receptors in cutaneous wound repair Cell Biochemistry and Function · 2014 · 68 citations
    3. Hairless is a nuclear receptor corepressor essential for skin function Nuclear Receptor Signaling · 2009 · 30 citations
    4. Expression and function of nuclear receptor co-activator 4: evidence of a potential role independent of co-activator activity Cellular and Molecular Life Sciences · 2012 · 26 citations
    5. Nuclear and cytosol Androgen Receptor in Androgen Dependent Dermatoses in Female Patients Experimental and Clinical Endocrinology & Diabetes · 2009 · 5 citations
    6. Detection of the nuclear translocation of androgen receptor using quantitative and automatic cell imaging analysis Tissue and Cell · 2024
    7. Melatonin regulates the periodic growth of secondary hair follicles through the nuclear receptor RORα Frontiers in Veterinary Science · 2023
    8. Hairless: A nuclear receptor corepressor essential for skin function Advances in developmental biology · 2006
    9. Side gland of Suncus murinus as a new model of sebaceous gland: 5?-reductase, androgen receptor, and nuclear androgen content in male and female animals Archives of Dermatological Research · 1989 · 7 citations
    10. Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease Endocrine Related Cancer · 2019 · 25 citations
    11. Progesterone Promotes Anti-Anxiety/Depressant-like Behavior and Trophic Actions of BDNF in the Hippocampus of Female Nuclear Progesterone Receptor, but Not 5α-Reductase, Knockout Mice International Journal of Molecular Sciences · 2025 · 4 citations
    12. Androgen binding profiles of two distinct nuclear androgen receptors in Atlantic croaker (Micropogonias undulatus) The Journal of Steroid Biochemistry and Molecular Biology · 2000 · 58 citations
    13. Expression of retinoid nuclear receptor superfamily members in human hair follicles and its implication in hair growth. Acta Dermato Venereologica · 1997 · 34 citations
    14. The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed Journal of bone and mineral research · 1998 · 1308 citations
    15. Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An <i>in Silico</i> and <i>in Vitro</i> Study Environmental health perspectives · 2020 · 29 citations
    16. Vitamin D Receptor: New Assignments for an Already Busy Receptor Endocrinology · 2006 · 510 citations
    17. Ligand-Independent Actions of the Vitamin D Receptor Maintain Hair Follicle Homeostasis Molecular Endocrinology · 2004 · 144 citations
    18. A Novel Point Mutation in the Ligand-Binding Domain (LBD) of the Human Glucocorticoid Receptor (hGR) Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus of hGR LBD in Conferring Transactivational Activity The Journal of Clinical Endocrinology & Metabolism · 2005 · 91 citations
    19. Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5<i>α</i>-Reductase Activity and Androgen Receptor Content* 1989 · 82 citations
    20. Membrane androgen receptors may mediate androgen reinforcement Psychoneuroendocrinology · 2010 · 37 citations
    21. Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching (FRAP) Is an Integrated Measure of Receptor Function Molecular Medicine · 2004 · 31 citations
    22. Allosteric interactions prime androgen receptor dimerization and activation bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 1 citations
    23. Molecular mechanisms of androgen receptor functions Data Archiving and Networked Services (DANS) · 2007
    24. Research on Expression of Retinoid-related Orphan Receptor (ROR) in the Skin of Cashmere Goat China Animal Husbandry & Veterinary Medicine · 2010
    25. A comprehensive investigation into the molecular mechanism responsible for selective androgen receptor (SARM) tissue-selectivity OhioLink ETD Center (Ohio Library and Information Network) · 2008
    26. Respiratory regulation by steroids in newborn rats: a sex‐specific balance between allopregnanolone and progesterone receptors Experimental physiology · 2017 · 17 citations
    27. Androgen receptor in rat liver: Characterization and separation from a male-specific estrogen-binding protein Archives of biochemistry and biophysics · 1989 · 24 citations
    28. Functional analyses of a novel missense and other mutations of the vitamin D receptor in association with alopecia Scientific Reports · 2017 · 20 citations
    29. 2,3,7,8‐Tetrachlorodibenzo‐<i>p</i>‐dioxin causes an increase in protein kinases growth hepatic associated with epidermal factor receptor in the plasma membrane Journal of Biochemical Toxicology · 1988 · 60 citations
    30. In situ detection of retinoid-X receptor expression in normal and psoriatic human skin 1995 · 42 citations