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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

A patient with Satoyoshi syndrome improved with a treatment combining several medications, including carbamazepine and methotrexate.

Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.

Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.

Menopausal acne is treated with medications and lifestyle changes, but careful choice is needed due to side effects.

Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.

PGF_2α receptors in human eyelids are found in specific parts of hair follicles, explaining eyelash changes with glaucoma treatment.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Androgens may worsen COVID-19 and hair loss could indicate the disease's severity.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

The gene Foxn1 is important for hair growth, and understanding it may lead to new alopecia treatments.

The document explains various skin conditions and their treatments.

The document concludes that treatments for female hair loss and excess body hair are available, but managing expectations is important.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Lactate production is important for activating hair growth stem cells.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.