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The document suggests a new model for evaluating public research that better captures the full value of knowledge creation and use, using PCOS research as an example.

Liposomal anthracyclines are effective and safer for treating multiple myeloma, especially in elderly patients.

St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.

Pulsed-intense light can significantly reduce hair, with effectiveness depending on treatment number and timing, and has mild side effects.

bFGF, VEGF, and minoxidil decrease collagen production in hair cells, possibly affecting hair growth.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.

Laser hair removal works well for people with dark hair and light skin, but it's less effective for light hair or dark skin; improvements are expected.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

Transgender patients need proper skin care, especially when undergoing hormone treatments, to manage issues like acne and hair loss.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

The 2018 update to the ED care model added a new severity score and stressed a detailed evaluation of both physical and psychological aspects.

Caffeine-based liquid 0.2% is as effective as minoxidil 5% for treating male hair loss.

Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.

Researchers identified specific genes that are important for mouse skin cell development and healing.

Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.

The conclusion is that understanding and addressing the psychological effects of alopecia areata is important for effective treatment.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.

Hair loss can lead to significant stigma and lower quality of life, especially for women and those with certain types of alopecia.