6 citations,
February 2004 in “Clinical and Experimental Ophthalmology” The document concludes that careful diagnosis is crucial for chromosome 13q deletion syndrome, tamoxifen can cause reversible eye damage, finasteride may be linked to cataracts, and OCT is useful for diagnosing macular diseases.
4 citations,
January 2012 in “Chemical Immunology” Some drugs, especially biologics, can cause skin reactions that look like other skin diseases, and stopping the drug usually helps clear up these reactions.
1 citations,
December 2016 Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.
1 citations,
October 2010 in “Cambridge University Press eBooks” Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.
May 2006 in “Women's Health Medicine” Excessive hair growth in women, often from high androgen levels, is usually caused by PCOS, and can be treated with hair removal, medication, and possibly weight loss.
July 2020 in “Journal of Cosmetic and Laser Therapy” Using your own platelet-rich plasma (PRP) can effectively treat hair loss, increasing hair density and width with no side effects.
March 2012 in “Hair transplant forum international” Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.
9 citations,
February 2022 in “Genes” Women with PCOS have more Bifidobacterium in their gut compared to those without PCOS.
24 citations,
September 2014 in “PloS one” Thyroid hormone receptors are essential for hair growth and wound healing.
10 citations,
January 2019 in “Archives of Endocrinology and Metabolism” Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.
1 citations,
January 1989 in “Handbook of experimental pharmacology” Anti-androgens can help reduce the effects of male hormones on the skin.
38 citations,
October 2005 in “Expert opinion on therapeutic patents” Selective androgen receptor modulators (SARMs) are a promising type of drug for various health conditions due to their targeted actions.
28 citations,
September 2000 in “Journal of Medicinal Chemistry” Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.
27 citations,
October 2001 in “Journal of Medicinal Chemistry” Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.
23 citations,
October 2008 in “Journal of medicinal chemistry” PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.
1 citations,
May 2001 in “Journal of Labelled Compounds and Radiopharmaceuticals” Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.
January 2022 in “Current Enzyme Inhibition” New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
53 citations,
June 1993 in “Proceedings of the National Academy of Sciences of the United States of America” LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
18 citations,
January 1998 in “Endocrine” RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.
13 citations,
August 1995 in “The Journal of Steroid Biochemistry and Molecular Biology” The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.
December 2020 in “Research Square (Research Square)” Rare ovarian tumors can cause increased male hormones in postmenopausal women; surgery is an effective treatment.
213 citations,
June 2017 in “Rheumatology” The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.
67 citations,
January 1987 in “The Journal of urology/The journal of urology” New hormonal therapies can help treat advanced prostate cancer but may cause testicular issues.
48 citations,
November 1992 in “International Journal of Dermatology” Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.
13 citations,
March 2019 in “Pharmacology Research & Perspectives” In Singapore, most skin reactions to drugs were in females and Chinese, often caused by painkillers, antibiotics, and some other drugs, with serious cases linked to genetics.
11 citations,
May 2010 in “Journal of Medicinal Chemistry” A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
7 citations,
August 2005 in “British Journal of Dermatology” Etanercept improved symptoms of a specific type of psoriatic arthritis in a patient who didn't respond to other treatments.
1 citations,
October 2017 in “Elsevier eBooks” Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.
1 citations,
February 2009 in “Journal of The American Academy of Dermatology” Children's Serum Sickness-Like Reaction is often linked to antibiotics, especially amoxicillin, and involves symptoms like rash, fever, and joint issues.
1 citations,
November 2008 in “Acta crystallographica” Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.