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Chemotherapy can cause significant hair thinning and changes in hair texture, while tamoxifen has a smaller effect.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Uncombable hair syndrome causes frizzy hair and can affect the nervous system, eyes, and ears, often co-occurring with other hair, skin, nail, and teeth conditions, and is linked to three specific gene mutations.

Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.

Scientists now better understand the genetics of hypohidrotic ectodermal dysplasia, leading to more accurate diagnoses and potential new treatments.

Different types of scarring alopecia may be stages of one disease, and accurate diagnosis is crucial to prevent permanent hair loss.

Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.

Stress, nutritional issues, and chronic diseases can cause hair loss, and nail changes may signal internal diseases; treatment focuses on the underlying cause.

Scalp cooling to prevent hair loss from chemotherapy works for some but not all, and studying hair damage markers could improve prevention and treatment.

Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.

Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.

The document explains different types of skin lesions and their characteristics, causes, and related conditions.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

RU 58841 may treat acne, hair loss, and excessive hair growth.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.

Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Genetics and hormones cause hair loss; finasteride treats it safely.

Higher androgen levels do not cause baldness in men.

Machine learning can predict symptoms and quality of life in chronic skin disease patients using smartphone app data, and shows that app use varies with patient characteristics.