Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that persistent significant alopecia was a common side effect following FEC-docetaxel chemotherapy, with a 33.4% global incidence, highlighting the need for awareness and potential preventative measures like cooling caps during treatment.

This study found that topical application of the BRAF inhibitor vemurafenib improved wound healing and promoted hair follicle regeneration in a diabetic murine model.

In this study, XMU-MP-1 unexpectedly reduced cell proliferation and altered cell cycle progression in a model human hair follicle, possibly due to off-target kinase inhibition.

New cancer treatments show promise in reducing tumor growth and improving skin regeneration in mice.

This study reports that hedgehog pathway inhibitors, sonidegib and vismodegib, showed distinct adverse event patterns in real-world data, suggesting the need for further research to confirm these findings.

In this retrospective study of eight Saudi children with hereditary vitamin D resistant rickets, researchers observed that adjunctive cinacalcet appeared safe and showed initial promise in improving serum PTH levels, though further investigation is needed to confirm its efficacy.

This study found that ALRN-6924, a clinical-stage dual inhibitor, can selectively protect human scalp hair follicles from paclitaxel-induced toxicity and damage by inducing transient cell cycle arrest in healthy cells without affecting cancer cells, potentially reducing chemotherapy-induced alopecia.

A man treated with gefitinib for lung cancer grew new hair on his bald scalp.

This study reported that dermatological adverse events are common in patients treated with amivantamab for non-small cell lung cancer, often impacting quality of life and requiring treatment modifications.

In a mouse model of chemotherapy-induced alopecia, this study found that enhancing ETV2 expression improved angiogenesis and hair regrowth following 5-fluorouracil treatment.

This report describes a 33-year-old woman who developed alopecia neoplastica due to gastric adenocarcinoma, highlighting the role of tumor invasion in hair follicle atrophy.

This review discusses anti-angiogenic therapy for cancer, highlighting VEGF blockers' effectiveness but also their limitations, such as resistance and adverse effects; it reports no new clinical results.

This study examined treatments for emesis in young Alexander disease patients, finding that 95% responded positively to valproic acid, which was more effective than anti-reflux medications or cyproheptadine, though some adverse effects require monitoring.

This review discusses the antiviral potential of cepharanthine against SARS-CoV-2, noting its effectiveness in preclinical models but presenting no new clinical results.

This study found that certain nutraceuticals did not interfere with tamoxifen's inhibition of estrogen in breast cancer cells and may enhance its effects, suggesting potential as an adjuvant therapy for hair loss in patients undergoing endocrine therapy.

Minoxidil not effective in preventing chemotherapy-induced hair loss.

This study will investigate the efficacy of YH0618 granules on reducing chemotherapy-induced hair loss in breast cancer patients, focusing on potential mechanisms related to kidney deficiency, with outcomes not yet reported.

In this study, the first case of a persistent curly hair phenotype was reported with nivolumab treatment in a patient with metastatic squamous cell lung cancer.

This phase Ib study found that combining pegylated liposomal doxorubicin and pembrolizumab was well-tolerated and effective, with durable antitumor responses and a median survival of over two years in heavily pretreated ER-positive metastatic breast cancer patients.

This case report describes a rare instance of alopecia areata linked to nivolumab treatment in a patient with hepatocellular carcinoma.

This review highlights that various targeted cancer therapies are associated with specific ocular side-effects, emphasizing the importance of awareness among ophthalmologists for timely diagnosis and management.

This article reviews naevus comedonicus, highlighting potential treatments like retinoic acid application and surgical intervention, but reports no new clinical findings.

This study found that Cepharanthine may mitigate doxorubicin-induced senescence by reducing SA-β-Gal activity and restoring autophagy in cell models, offering insights for antiaging drug development.

Using a niacinamide cream can improve life quality for breast cancer patients during chemotherapy.

Hair loss is a common but often unreported side effect of cancer treatments, especially for breast and prostate cancers.

This study reports that Elvitegravir, a drug currently approved for other uses, shows potential as a neuro- and mitoprotective agent by attenuating mitochondrial damage caused by NMDA receptors in primary mouse cortical neurons.

This study observed that pantethine, a vitamin B5 precursor, attenuates tumor growth in immunocompetent mice by enhancing antitumor immunity, but its effect is limited by immune cell exhaustion over time.

This study found that Nourkrin significantly improved hair growth in individuals with hair loss and was well-tolerated, suggesting it may be a viable alternative to pharmacotherapy for androgenetic alopecia.