research Compartmentalized Organization: A Common and Required Feature of Stem Cell Niches?
Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
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research Neuroactive Steroid Levels and Psychiatric and Andrological Features in Post-Finasteride Patients
Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.
research Oxidative Damage Control in a Human Mini-Organ: Nrf2 Activation Protects Against Oxidative Stress-Induced Hair Growth Inhibition
Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.
research A Neuroendocrinological Perspective on Human Hair Follicle Pigmentation
Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
research Stem Cell Secretome as a New Booster for Regenerative Medicine
Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.
research Botulinum Toxin Off-Label Use in Dermatology: A Review
Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
research Cannabinoids: Current and Future Options to Treat Chronic and Chemotherapy-Induced Neuropathic Pain
Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.
research Alopecia Areata Update
Despite progress in treatment, the exact cause of Alopecia areata is still unknown.
research Hair Pain (Trichodynia): Frequency and Relationship to Hair Loss and Patient Gender
Hair pain is more common in women with hair loss, but it's not linked to the cause or severity of hair loss.
research Skin Disorders in Parkinson’s Disease: Potential Biomarkers and Risk Factors
Certain skin conditions may indicate or increase the risk of Parkinson's disease.
research Types of Hair Loss and Treatment Options, Including the Novel Low-Level Light Therapy and Its Proposed Mechanism
Hair loss treatments include medications and new methods like low-level light therapy, which may work by boosting cell activity and blood flow.
research The Non-Neuronal and Nonmuscular Effects of Botulinum Toxin: An Opportunity for a Deadly Molecule to Treat Disease in the Skin and Beyond
Botulinum toxin has potential for treating various skin conditions and improving wound healing.
research Primary Cicatricial Alopecia: Recent Advances in Understanding and Management
New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.
research Environmental Stress But Not Subjective Distress in Children or Adolescents With Alopecia Areata
Kids with alopecia areata may experience more stress but not necessarily feel more anxious or depressed than others.
research Spinal and Bulbar Muscular Atrophy: Pathogenesis and Clinical Management
Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.
research Therapeutic Strategies for Treating Hair Loss
The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
research Psychodermatology: Emotional Factors and Treatment Approaches
The review suggests that understanding and treating the psychological aspect of skin disorders is important and calls for more collaboration in this field.
research Investigation of Suicidality and Psychological Adverse Events in Patients Treated With Finasteride
Finasteride may cause suicidal thoughts and mental side effects, especially in young people with hair loss.
research Realizing the Therapeutic Potential of Neuroactive Steroid Modulators of the GABAA Receptor
Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
research Post-Finasteride Syndrome and Post-SSRI Sexual Dysfunction: Two Sides of the Same Coin?
PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.
research Design of a RADA16-Based Self-Assembling Peptide Nanofiber Scaffold for Biomedical Applications
RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
research Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle
Ephrins slow down skin and hair follicle cell growth.
research Live Imaging of Stem Cells: Answering Old Questions and Raising New Ones
Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
research Eccrine Sweat Glands Associate With the Human Hair Follicle Within a Defined Compartment of Dermal White Adipose Tissue
Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.
research Vasoactive Intestinal Peptide, Whose Receptor-Mediated Signaling May Be Defective in Alopecia Areata, Provides Protection from Hair Follicle Immune Privilege Collapse
A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.
research Basics of Androgen Synthesis and Action
Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
research Destruction of the Arrector Pili Muscle and Fat Infiltration in Androgenic Alopecia
Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.
research Side Effects of 5-Alpha Reductase Inhibitors: A Comprehensive Review
5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.
research Finasteride Treatment Inhibits Adult Hippocampal Neurogenesis in Male Mice
Finasteride reduces new brain cells in male mice, possibly causing depression.
research New Steps Forward in the Neuroactive Steroid Field
Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.