research Systemic Antifungals: Overview, Applications, and Costs
Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.
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research Cytostatics and Immunosuppressive Drugs: Toxicities and Management
Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.
research Trichoscopic Findings and Quality-of-Life Assessment in Egyptian Patients with Noncicatricial Alopecia
Hair loss in Egyptian patients without scarring was studied, and it was found to significantly affect their quality of life.
research Managing Azathioprine-Induced Myelosuppression and Alopecia Totalis: Lessons from a Systemic Lupus Erythematosus Patient
Monitor for early signs of myelosuppression, like hair loss, in patients on azathioprine to manage side effects.
research Understanding, Recognizing, and Managing Toxicities of Targeted Anticancer Therapies
Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
research Optimizing Treatment Management of Trastuzumab Deruxtecan in Clinical Practice of Breast Cancer
Trastuzumab deruxtecan is effective for HER2-positive breast cancer but requires careful management of side effects.
research Presumptive Albendazole Toxicosis in 12 Alpacas
High doses of albendazole can be deadly for alpacas.
research The Impact of Chemotherapy on the Nutritional Status of Breast Cancer Patients
Chemotherapy worsens nutritional status in breast cancer patients, requiring targeted nutritional strategies.
research Atypical Folliculitis Caused by Malassezia spp. in Immunosuppressed Patients
Some immunosuppressed patients can get unusual skin infections from Malassezia, which can be treated with antifungal medication.
research Chemotherapy for Children with Medulloblastoma
Chemotherapy may help with survival in children with medulloblastoma, but more research is needed.
research Permanent Chemotherapy-Induced Alopecia: Case Report and Review of the Literature
Some chemotherapy can cause permanent hair loss.
research First-In-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
research Alisertib Is Active as Single Agent in Recurrent Atypical Teratoid Rhabdoid Tumors in Four Children
Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.
research First-Line Therapy with Gemcitabine and Paclitaxel in Locally Recurrent or Metastatic Breast Cancer: A Phase II Study
Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.
research Role of Ferritin, Vitamin D, and Thyroid Dysfunction in Telogen Effluvium Among the Hospital Population in Western Saudi Arabia: A Case-Control Study
Low ferritin, vitamin D deficiency, and thyroid problems may contribute to hair loss in some hospital patients in Western Saudi Arabia.
research Granulocyte Colony-Stimulating Factor Treatment of Cyclic Neutropenia with Recurrent Oral Aphthae
G-CSF effectively treated a teenager's cyclic neutropenia and reduced her symptoms without adverse effects.
research Presumed Ocular Candidiasis in Drug Misusers After Intravenous Use of Oral High Dose Buprenorphine (Subutex)
Drug misuse can cause serious eye infections and other severe side effects.
research Bilateral Non-Specific Orbital Inflammation (Orbital Pseudotumor), Posterior Scleritis, and Anterior Uveitis Associated with Hypothyroidism in a Child
Intralesional cidofovir might be a viable alternative treatment for certain conditions.
research Acquired Ocular Toxoplasmosis in Pregnancy
Surgical excision is the best treatment for SCC, but intralesional cidofovir might be a good alternative.
research Bilateral Anterior Uveitis as a Presenting Manifestation of Sarcoidosis and Syphilis
Surgical excision is the best treatment for SCC.
research Tangent Screens Are Still Useful in the Assessment of Vigabatrin-Induced Visual Field Defects
Tangent screens help detect visual field defects from vigabatrin.
research Oculoplastic Surgery Atlas: Eyelid Disorders
Surgical excision is the best treatment for SCC, but intralesional cidofovir might be a viable alternative.
research Life-Threatening Macrophage Activation Syndrome as the Initial Presentation of Systemic Lupus Erythematosus: A Case Report and Review of the Literature
Macrophage activation syndrome can be a deadly first sign of systemic lupus erythematosus.
research Fever And Rash As Initial Signs Of Systemic Autoimmune Disease: Case Report
Fever and rash can be early signs of lupus.
research Cytokines
Cytokines are important for immune responses and treating diseases, but they can cause side effects like fever and skin issues.
research Toxic Epidermal Necrolysis
Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.
research Sweet Syndrome as the Presenting Symptom of Relapsed Hairy Cell Leukemia
Sweet syndrome can be the only sign of hairy cell leukemia relapse.
research Innovative Sequence of Docetaxel–Gemcitabine Based on Preclinical Data in the Treatment of Advanced Non-Small Cell Lung Cancer: A Phase I Study
The new chemotherapy combination for advanced lung cancer showed a 35.7% response rate but caused significant side effects.
research Oral Signs of Hematologic Disease
The conclusion is that different blood diseases cause specific oral symptoms and require varied treatments to manage these symptoms and improve patient health.
research Use of a Healthcare Claims Database for Post-Marketing Safety Assessments of Eribulin in Japan: A Comparative Assessment with a Prospective Post-Marketing Surveillance Study
Healthcare claims databases can help monitor drug safety, but may report adverse events differently than direct surveillance.