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Long-term high testosterone levels can improve bone density and reduce body fat but may increase the risk of prostate cancer and high blood pressure.

Vitamin D is important for bones, hair, blood pressure, and breast development.

The document concludes that respectful, gender-affirming healthcare improves mental health and encourages continued medical care for transgender and non-binary individuals.

Topical minoxidil is the best-supported treatment for female hair loss, but personalized plans are needed.

Lipedema is a painful fat disorder in women that's hard to treat, often worsens with hormonal changes, and requires symptom-focused therapies.

New biomaterial treatments for baldness show promise, with options depending on patient needs.

No single treatment is clearly effective for central serous chorioretinopathy.

New understanding and treatments for hair loss are improving, but more research is needed.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Androgen use may increase the risk of stroke, but more research is needed.

The skin's microbiome helps hair regrow by boosting certain cell signals and metabolism.

Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.

Shift work disrupts the body's natural clock, leading to health problems.

Myoblast transplantation shows promise for treating various muscle and heart conditions.

Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.

Environmental pollutants can damage hair health and cause hair loss.

Hair loss can significantly impact a person's mental health, causing issues like anxiety and depression, and stress can trigger hair loss.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.

Minoxidil can be effectively encapsulated in coated nanovesicles for potential drug delivery.

A pregnant woman with Werner's syndrome died during childbirth, but her baby survived and did not have the syndrome.

Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.

Surgical robots have improved but still can't perform tasks or make decisions on their own.

Neuregulin3 affects cell development in the skin and mammary glands.

Eclipta alba extract was found to be effective in promoting hair growth in hairless mice.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

Long-term anabolic steroid use can lead to heart and metabolic health issues.