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Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.

Copper treatments increase copper in all tissues, but brindled female mice accumulate much more copper in their kidneys without clinical effects, unlike brindled male mice where brain copper deficiency is clinically significant.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

AXR3 and SHY2 genes control the growth and timing of root hair development in plants.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Fatty acid transport protein 4 is essential for skin and hair development.

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

Cancer development is like natural selection, involving mutated cells and environmental factors.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.

Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.

Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.

The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.

Mice can correct hair follicle orientation without certain genes, but proper overall alignment needs those genes.

Autophagy is crucial for normal sebaceous gland function and sebum composition.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

GasderminA3 is important for normal hair cycle transitions by controlling Wnt signaling.

Leptin helps start the growth phase of hair.

Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.