research Destruction of the arrector pili muscle and fat infiltration in androgenic alopecia
This study found that in androgenic alopecia, the arrector pili muscle degenerates and is replaced by fat, unlike in normal skin or telogen effluvium.
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30 / 1000+ results research Tissue engineering strategies combining molecular targets against inflammation and fibrosis, and umbilical cord blood stem cells to improve hampered muscle and skin regeneration following cleft repair
This review discusses molecular and cellular strategies to improve muscle and skin regeneration and reduce scarring after cleft lip repair, offering potential benefits for function and aesthetics.
research Pro-Insulin-Like Growth Factor-II Ameliorates Age-Related Inefficient Regenerative Response by Orchestrating Self-Reinforcement Mechanism of Muscle Regeneration
This study demonstrated that supplementing aged mice with pro-IGF-II improved muscle regeneration by enhancing satellite cell proliferation and reducing adipogenesis, suggesting potential benefits for treating muscle injuries in elderly individuals.
research Long-Term Superiority of Composite Versus Muscle-Only Free Flaps for Skull Coverage
This study found that muscle-only free flaps for skull coverage were associated with serious complications, suggesting that composite or thicker muscle flaps may reduce these risks.
research Single follicular unit transplantation reconstructs arrector pili muscle and nerve connections and restores functional hair follicle piloerection
This study reports that transplanted mouse hair follicles restored piloerection ability and connected properly with host tissues, suggesting potential for advanced hair restoration therapies.
research Nestin-Expressing Stem Cells from the Hair Follicle Can Differentiate Into Motor Neurons and Reduce Muscle Atrophy after Transplantation to Injured Nerves
This study suggests that nestin-expressing hair follicle stem cells, when transplanted into transgenic mice with sciatic nerve injury, can differentiate into motor neurons and reduce muscle atrophy.
research Dynamic Transcriptome Profile Analysis of Mechanisms Related to Melanin Deposition in Chicken Muscle Development
In this study, researchers identified key genes such as EDNRB2, GPNMB, TRPM1, TYR, and DCT that regulate melanin deposition in the breast muscles of black-boned chickens, contributing to their unique pigmentation during embryonic development.
research The Anti-Muscle Atrophy Effects of Ishige sinicola in LPS-Induced C2C12 Myotubes through Its Antioxidant and Anti-Inflammatory Actions
This study found that Ishige sinicola ethanol extract and its butanol fraction can protect against lipopolysaccharide-induced muscle atrophy in C2C12 myotubes through antioxidant and anti-inflammatory activities.
research Adipose Infiltration of the Dermis, Involving the Arrector Pili Muscle, and Dermal Displacement of Eccrine Sweat Coils: New Histologic Observations in Frontal Fibrosing Alopecia
This study discovered that adipose tissue infiltration at the isthmus level appears significantly more often in frontal fibrosing alopecia cases compared to controls, suggesting a potential role in the condition's pathology.
research Muscle weakness of the lower limbs after epidural anesthesia in a pregnant woman with undiscovered systemic lupus erythematosus
This case report highlights the missed diagnosis of systemic lupus erythematosus in a pregnant woman, leading to her death despite treatment efforts after cesarean section and epidural anesthesia complications.
research Muscle pain in a woman with congenital adrenal hyperplasia due to 21-hydroxylase deficiency resolved with testosterone therapy. A case report with 10 years of follow-up
In this case study, a woman with congenital adrenal hyperplasia experienced substantial improvement in musculoskeletal and neurobehavioral symptoms after low-dose testosterone therapy, highlighting its potential role in managing chronic glucocorticoid overtreatment effects.
research Skin physiology in microgravity: a 3-month stay aboard ISS induces dermal atrophy and affects cutaneous muscle and hair follicles cycling in mice
In this study, mice exposed to prolonged space conditions demonstrated skin atrophy, altered hair follicle cycles, and significant changes in the gene expression associated with skin muscle health.
research Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism
This study observed that partial autotaxin deficiency in mice protects against diet-induced obesity and systemic insulin resistance, suggesting the ATX-LPA pathway negatively affects skeletal muscle insulin signaling and mitochondrial function during obesity.
research Beyond goosebumps: Does the arrector pili muscle have a role in hair loss?
This review summarizes the anatomy and physiology of the arrector pili muscle and discusses its potential role in hair loss disorders, reporting no new clinical results.
research Three-dimensional ultrastructural analysis of human skin with the arrector pili muscle interacting with the hair follicle epithelium
In this study, researchers developed a three-dimensional ultrastructural analysis tool using serial block-face scanning electron microscopy to reveal detailed nerve networks and muscle structures in human skin tissues, demonstrating the technique's potential to study structural changes in aging or disease.
research Multiple congenital smooth muscle hamartoma: A case report
This article describes a 10-month-old female with congenital smooth muscle hamartoma, highlighting the importance of differential diagnosis in congenital skin lesions due to potential malignancy risks.
research Curly Hair Follicle is Sculpted by a Contracted Arrector Pili Muscle. A Hypothesis with Treatment Implications
This study hypothesizes that the curling of hair may result from the contraction of the Arrector Pili Muscle, contributing to the diverse types of curly hair.
research Curly Hair Follicle is Sculpted by a Contracted Arrector Pili Muscle. A Hypothesis with Treatment Implications
This study hypothesizes that curly hair is shaped by the contraction of the Arrector Pili Muscle within the follicle, potentially modifiable through muscle-relaxing treatments, but further research is needed to confirm this mechanism.
research Acquired smooth muscle hamartoma with sebaceous component
This case report describes an 18-year-old male with a rare acquired smooth muscle hamartoma on his face, characterized by hyperpigmented plaques and increased hair growth, suggesting a histological overlap with folliculosebaceous cystic hamartoma.
research Bead-jet printing enabled sparse mesenchymal stem cell patterning augments skeletal muscle and hair follicle regeneration
This study found that a new "bead-jet" printing system for mesenchymal stem cells in Matrigel beads improved skeletal muscle regeneration and skin healing in a high-density, sparse pattern.
research Hair Follicle-Derived Smooth Muscle Cells and Small Intestinal Submucosa for Engineering Mechanically Robust and Vasoreactive Vascular Media
This study found that combining hair follicle-derived smooth muscle cells with a natural biomaterial created vascular constructs with mechanical and functional properties similar to native arteries, suggesting potential for arterial implantation.
research Long-term Oral Administration of 5α-reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats
Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.
research Comparative transcriptomic analysis of dermal wound healing reveals de novo skeletal muscle regeneration in Acomys cahirinus
In this study, researchers observed that African spiny mice, Acomys cahirinus, are capable of regenerating skeletal muscle in dermal wound sites, unlike common mice, Mus musculus.
research Human hair follicle stem cell differentiation into contractile smooth muscle cells is induced by transforming growth factor-β1 and platelet-derived growth factor BB
In this study, researchers developed a method to efficiently derive contractile smooth muscle cells from human hair follicle stem cells using TGF-β1 and PDGF-BB, which may advance vascular tissue engineering.
research The Muscle Immobility of Depression—The Weightlessness Within
This study observed that individuals with major unipolar depression have higher levels of sodium and potassium in their hair and decreased antidiuretic hormone levels, similar to changes seen in astronauts after space missions.
research Urinary Incontinence due to Overactive Detrusor Muscle: A Rare Side Effect of Venlafaxine
This case report describes a 66-year-old male with benign prostatic hyperplasia who developed urinary incontinence after starting venlafaxine, which resolved upon discontinuation of the medication.
research Changes in the Expression of Smooth Muscle Cell–Related Genes in Human Dermal Sheath Cup Cells Associated with the Treatment Outcome of Autologous Cell–Based Therapy for Male and Female Pattern Hair Loss
This study found variable outcomes in hair loss treatment with autologous cell-based therapy using DSC cells, with certain gene markers showing inconsistent correlations with treatment efficacy.
research Androgen-induced norepinephrine release in male accessory sex organ smooth muscle growth and differentiation
This review discusses the role of norepinephrine release and protein kinase C activation in the development of benign prostatic hypertrophy, suggesting potential targets for new therapies, but it reports no new clinical results.
research Hair follicle associated pluripotent (HAP) stem cell from young mice have the greatest potential to differentiate to cardiac muscle cells
This study found that the ability of hair-follicle-associated pluripotent stem cells to differentiate into cardiac muscle cells decreased sharply with age in mice, suggesting early stem cell banking for future regenerative treatments.
research Smooth muscle cell expression of a constitutive active form of human Profilin1 accelerates cutaneous wound repair
This study found that profilin1 protein significantly accelerated wound healing in transgenic mice by reducing wound size and enhancing vascularization and cell migration compared to nontransgenic and 88R/L mice.