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January 2009 in “Drug delivery system” This article provides a detailed review of minoxidil's pharmacological effects for treating androgenic alopecia but reports no new clinical results.
July 2026 in “Preprints.org” This review outlines the optimization of platelet concentrates for hair loss treatment and suggests extracellular vesicles as a key future element, aiming to advance point-of-care regenerative therapies despite the need for a unified framework and further research on underlying mechanisms.
July 2026 in “Skin Appendage Disorders” This review highlights that poor therapeutic responses in female pattern hair loss involve multiple factors, including pharmacogenetic influences and comorbidities. It suggests a framework to improve outcomes by identifying the primary contributors and using personalized treatment strategies.
July 2026 in “Scholars Journal of Medical Case Reports” This case study reports a rare coexistence of alopecia areata and lichen planopilaris in a 37-year-old woman and highlights the importance of targeting active scalp areas for biopsy to appropriately manage coexisting scarring and non-scarring alopecias, with distinct therapeutic priorities.
July 2026 in “Anais Brasileiros de Dermatologia” This study reported that both AGA and SD in Caucasian male patients showed overlapping histopathological features with FAPD, particularly perifollicular fibrosis and inflammation, complicating diagnosis.
June 2026 in “Skin Appendage Disorders” This review discusses diffuse unpatterned alopecia (DUPA) as an understudied variant of androgenetic alopecia, summarizing its presentation and management while calling for further research to better understand its distinct characteristics.
June 2026 in “International Journal of Drug Delivery Technology” This study highlights the potential of polymeric micelles in enhancing the targeted delivery and efficacy of treatments for androgenetic alopecia, by offering improved retention on the scalp, extended release, and reduced systemic side effects compared to conventional therapies like minoxidil and finasteride.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study utilized computational approaches to screen natural compounds targeting a non-androgen pathway involving PIEZO1 and MLCK for treating androgenetic alopecia, identifying several potential candidates for further validation but making no clinical claims.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This in silico study identified potential natural product compounds targeting a non-androgen pathway for promoting hair growth, but further laboratory validation is necessary before any clinical claims can be made.
April 2026 in “Canadian Medical Association Journal” This study reported that androgenetic alopecia in women becomes more prevalent with age, with risk factors including heredity and endocrine disorders, and differs clinically from male-pattern hair loss by causing diffuse hair thinning rather than loss at the temples or crown.
This study suggests that bio-nanovesicles, such as exosomes and microvesicles, may enhance skin and hair follicle regeneration by modulating key signaling pathways, potentially overcoming the limitations of conventional treatments for alopecia and chronic skin diseases.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review synthesizes current knowledge on hair follicle biology in androgenetic alopecia and explores potential regenerative therapies, but it reports no new clinical results.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This narrative review explores molecular signaling pathways and their impact on hair follicle microenvironments in androgenetic alopecia, alongside potential treatments like stromal vascular fraction therapies and exosome-based strategies.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review integrates current understanding of hair follicle biology and signaling pathways into a comprehensive framework for androgenetic alopecia, but presents no new empirical findings.
This study reviews female hair loss conditions with a focus on diagnosis and treatment. It highlights female pattern hair loss as the most common form and emphasizes the need for personalized therapy, including topical minoxidil and, when appropriate, antiandrogen treatments.
March 2026 in “Editora Pasteur eBooks” This chapter provides a comprehensive review of androgenetic alopecia, covering its key physiological mechanisms, diagnostic methods, and a variety of treatment options ranging from topical therapies to aesthetic and regenerative procedures, emphasizing recent advances observed in dermatological practice.
March 2026 in “PubMed Central” This study reports that the prevalence of female pattern hair loss increases with age, affecting 12% of women by age 29, 25% by age 50, and 41% to 50% by age 70 and older, with risk factors including genetics and certain endocrinological conditions.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reviewed treatments and findings related to male androgenetic alopecia, noting that topical minoxidil and oral finasteride are effective for slowing hair loss, while newer interventions like PRP and microneedling show promise.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses the epidemiology, pathophysiology, diagnosis, and management of male androgenetic alopecia, noting that combination treatments, including FDA-approved and emerging therapies, may improve outcomes without added side effects.
February 2026 in “Editora Pasteur eBooks” An integrative approach combining medical, nutritional, and lifestyle changes effectively manages female pattern hair loss.
February 2026 in “Nano Research” This study developed a dissolvable microneedle system delivering specific molecules to remodel lymphatic networks and normalize metabolic processes, which accelerated hair growth and activated hair follicle stem cells in a mouse model of androgenetic alopecia.
January 2026 in “Biology” This review discusses the complex genetic factors contributing to androgenetic alopecia, highlighting the variability in genetic risk across different populations and the emerging understanding of personalized treatment strategies, but reports no new clinical findings.
January 2026 in “Journal of Investigative Dermatology” Female-pattern hair loss may involve an autoimmune-like process, suggesting new treatment options.
January 2026 in “Journal of Hair Restoration and Regenerative Medicine” This review discusses methods to better identify unsafe donor areas in patients with diffuse unpatterned alopecia, emphasizing non-surgical management when specific diagnostic criteria are met, but reports no new clinical results.
January 2026 in “Open MIND” This study identified candidate compounds from a natural-product library that may interact with the PIEZO1 and MLCK pathways, potentially countering a non-androgen cause of hair follicle miniaturization, all based on computer simulations; experimental validation is necessary.
January 2026 in “OSF Preprints (OSF Preprints)” In this study, researchers presented a novel therapeutic approach for androgenetic alopecia combining AR-PROTAC degradation with regenerative strategies and evaluated the potential of GT20029 as a topical treatment, proposing a three-phase protocol and future research hypotheses.
The authors discussed the potential benefits of Urtica dioica and Serenoa repens for hair health, but emphasized that more concrete evidence and standardized formulations are necessary for reliable therapeutic use.
January 2026 in “Dermatology Review” This review discusses androgenetic alopecia, outlining its genetic and hormonal causes, and summarizes current and emerging treatments like minoxidil, finasteride, and low-dose oral therapies, emphasizing the need for more research to confirm the efficacy and safety of newer approaches.
December 2025 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” This study compared the diagnostic effectiveness of Folliscope and Trichoscope in 100 men with androgenetic alopecia, concluding that using both methods enhances diagnostic accuracy by providing complementary insights—Trichoscope highlights patterns while Folliscope offers objective measurements.
December 2025 in “Cosmetics” This review synthesizes recent molecular and preclinical advances in alopecia areata and androgenetic alopecia, highlighting how interventions targeting specific intracellular signaling pathways and utilizing stem cell technologies can support precision regrowth and structural follicle reconstruction.