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The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.

Botanical extracts are increasingly important in cosmetics and drugs for their effectiveness and safety, backed by traditional use and scientific evidence.

Double trichophytic closure effectively repairs thin scalp scars, reducing financial burden.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The Rotterdam Study aims to understand various diseases in older adults.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Fungi-produced compounds can change plant root growth.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Oestrogens are key for bone growth during puberty in both boys and girls.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.