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This study developed finite element models to examine skin's biomechanical properties, finding that structural heterogeneities like Rete ridges and hair follicles create distinct stress and strain patterns that may influence mechanosensation and skin integrity.

Hair follicles form hard α-keratin filaments in four steps, showing structural differences.

This study found that the weak tensile strength of pili torti hair may result from loose keratin intermediate filaments due to abnormalities in disulfide bonds.

The hair follicle structure is more complex than thought, with new findings on protein formation.

This review discusses new developments in understanding the structure and properties of keratin fiber cell membrane complexes, without reporting new experimental results.

This study suggests that the C-terminal of AHF is crucial for its binding to keratin bundles and modulating the keratin meshwork in hair follicles.

This study suggests that the interaction between folliculin and plakophilin-4 (p0071) may play a role in folliculin's tumor suppressor function by regulating RhoA signaling, impacting cell migration and junction formation.

This study reports that a 190,000 molecular weight protein, identified as trichohyalin, may play a matrix role in the development of inner root sheaths in hair follicles.

This study used fibre optic confocal imaging to visualize subsurface structures in live mouse skin, revealing cellular details and blood vessel networks that dynamic events could be studied in vivo.

This study suggests that the expression patterns of keratin and filaggrin indicate milia may originate from the outermost cells of the hair bulge in the outer root sheath.

This study suggested that MRF may support skin regeneration and rejuvenation by promoting collagen synthesis and regulating factors involved in fibroblast activation and ECM remodeling, with preliminary findings indicating ADSCs might aid these processes.

This study found that electrospun short fibrous sponges effectively mimic the 3D extracellular matrix, promoting tissue regeneration, angiogenesis, and wound healing in diabetic rats better than 2D fiber membranes.

In this review, the researchers highlight the role of fibroblasts in regulating the extracellular matrix and immune responses, emphasizing the impact on macrophages and potential therapeutic insights for fibrotic diseases and cancer.

This study observed that Nod factor stimulation in alfalfa roots leads to dynamic changes in the cytoskeleton and endoplasmic reticulum, suggesting a mechanism for root hair growth changes.

This study found that ECMs from papillary and dermal papilla fibroblasts support normal basement membrane formation, suggesting potential improvements for therapeutic biomaterials in skin engineering.

This review discusses the role of intermediate filaments in cell signaling and differentiation, emphasizing their impact on stem cell function, development, and disease, but reports no new clinical results.

In this study, microporous electrospun scaffolds pre-seeded with dermal fibroblasts accelerated wound healing and improved dermal matrix structure and hair follicle regeneration compared to acellular scaffolds in a rat model.

This study found that the formation of the fibre cuticle surface in Merino sheep is similar to the epidermal stratum corneum process and not from a modified plasma membrane as previously thought.

This study found that Mueller Matrix microscopy can accurately identify, detect, and evaluate hair follicles in mouse skin tissue, suggesting its potential for skin structure research and dermatological applications.

This study found that fibroblast behavior switching between proliferation and ECM deposition is vital for dermal architecture, where cell migration is primarily important for tissue repair during wound healing.

The researchers reported that basement membrane heterogeneity, especially laminin α5 composition, plays a critical role in distinct inter-tissue interactions and hair cycle regulation in mouse hair follicles.

This study explored the development of GelMet, an electrospun hybrid nanofiber scaffold made from gelatin and PEG methacrylate, which demonstrated strong mechanical properties and effectively supported cell growth in vitro, suggesting its potential for skin tissue engineering applications.

This study identified collagen XXII as a novel extracellular matrix protein specifically present at tissue junctions, where it functions as a cell adhesion ligand for skin epithelial cells and fibroblasts.

This paper presents a new methodology combining magnetic tweezers and traction force microscopy to study keratinocyte mechanobiology, but reports no experimental results yet.

Using synchrotron X-ray imaging, this study mapped the complex innervation of male rat vibrissa follicles, revealing distinct types of myelinated afferent neurons and patterns of axonal organization that may inform sensory processing in the brainstem.