January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Some African American women experience central scalp hair loss, often linked to a history of fungal scalp infection.
March 2023 in “The primary care companion for CNS disorders” Dengue fever can cause hair loss that may lead to serious psychological issues like Body Dysmorphic Disorder in young women.
July 2025 in “Journal of Investigative Dermatology” Miniaturized hair follicles in androgenetic alopecia show abnormal mitochondrial activity and damage.
August 2023 in “Authorea (Authorea)” This article highlights that tinea capitis, a fungal scalp infection primarily seen in children, is often misdiagnosed in adults, especially postmenopausal women and immunocompromised individuals, leading to unnecessary treatments and potential permanent hair loss if not correctly identified and treated.
5 citations
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June 2021 in “Journal of neurology, neurosurgery and psychiatry” This study found that females exposed to high cumulative doses of cyproterone acetate had a 6–20 fold increased risk of developing meningiomas compared to those on lower doses.
May 2024 in “Journal of Fungi” This review reports that tinea capitis is uncommon in adults, with postmenopausal African American or Black women at higher risk, and emphasizes the importance of prompt antifungal treatment to prevent complications.
December 2024 in “Annals of Medicine and Surgery” Early diagnosis of pseudopelade of Brocq in men is crucial to prevent permanent hair loss.
October 2024 in “Developmental Dynamics” This paper highlights advances in Developmental Dynamics, noting how epoa-deficient zebrafish can model Diamond-Blackfan anemia like disorders for drug screening, Alx4 mouse models offer insights into craniofacial development, and mTORC1 signaling is crucial for retinal development.
2 citations
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August 2024 in “Molecular Genetics & Genomic Medicine” In this case study, an 8-day-old neonate with holocarboxylase synthetase deficiency showed dramatic improvement in lactic acidosis and overall clinical condition following biotin mega-dose therapy, highlighting the importance of early genetic testing and timely treatment in such metabolic disorders.
February 2025 in “La Pediatria Medica e Chirurgica” In this case study, a 12-year-old boy with Cushing's Disease experienced a complex diagnostic journey; ultimately, a left-side ACTH-secreting microadenoma was identified and treated with gamma knife therapy, normalizing hypercortisolism but resulting in growth hormone deficiency.
July 2024 in “Indian Dermatology Online Journal” In this case study, a 45-year-old immunocompetent woman with tinea capitis exhibited an unusual presentation of the infection with a scaly plaque and hair loss, which responded well to treatment with itraconazole.
3 citations
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February 2012 in “The American Journal of Dermatopathology” This report documents the first known case of cutaneous mastocytosis associated with congenital alopecia areata in a young Korean girl, confirmed through histopathological examination.
21 citations
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October 2009 in “Molecular Biology Reports”
5 citations
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September 2012 in “Journal of Investigative Dermatology” This study found that knocking down P-cadherin expression in cultured human hair follicles recreates the hair abnormalities seen in patients with hypotrichosis with juvenile macular dystrophy.
102 citations
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January 2020 in “Recent Patents on Inflammation & Allergy Drug Discovery” In this article review, it was reported that systemic oral antifungal treatments are essential for effectively managing tinea capitis, as topical antifungals alone cannot reach the hair follicle roots but may reduce spore transmission when used alongside oral medications.
March 2024 in “Frontiers in endocrinology” This study reports the first case of mandibuloacral dysplasia syndrome associated with MTX2 gene mutation in the Chinese population, expanding the known spectrum of MTX2 mutations.
14 citations
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January 2018 in “Endocrine” This report describes a three-generation family with Cantú syndrome linked to a novel ABCC9 gene variant, featuring acromegaloid appearance and hypertrichosis without growth hormone abnormalities, and suggests a potential association with pituitary adenomas.
In a case report, this study identified a new genetic variant in a six-year-old girl from Saudi Arabia with hypotrichosis and juvenile macular dystrophy, expanding the understanding of the genetic spectrum of this rare condition in the region.
September 2024 in “Frontiers in Genetics” In this study, researchers found a significant association between the rs13405699 SNP at 2q31.1 and male pattern baldness among Han Chinese men, suggesting genetic influence on this condition in this population.
September 2024 in “PubMed” This case reported that a 6-year-old patient with scalp lesions, diagnosed with tinea capitis and head lice, successfully responded to a new treatment regimen including griseofulvin, permethrin, and prednisolone, highlighting the need for better diagnosis and interprofessional communication.
January 2018 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” Scalp micropigmentation is a process where tiny dots of pigment are tattooed onto the scalp to create the appearance of a shaved head or fuller hair.
January 2016 in “Case reports in clinical medicine” This article discusses monilethrix in a 6-year-old girl, explores various aspects of the disease, and its treatment, but reports no new clinical results.
28 citations
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November 2018 in “Journal of cellular physiology” This study found that miR-124 may facilitate the differentiation of hair follicle stem cells into neuronal cells by targeting Sox9 and Ptbp1.
6 citations
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August 2012 in “The Journal of Pediatrics” This case report describes a 12-year-old girl diagnosed with monilethrix, characterized by fragile, beaded hair shafts, with no effective treatment currently available.
December 2025 in “PLoS ONE” In this study, among Chinese infants and young children aged 0-5 years, Type II and Type III frontal hairline patterns were the most common, with a negative correlation observed between age and hairline type.
May 2024 in “Clinical, cosmetic and investigational dermatology” This case report describes an adolescent boy with congenital triangular alopecia who showed significant hair regrowth after eight months of treatment with 5% topical minoxidil, achieving full coverage of the affected area without adverse effects.
23 citations
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October 2021 in “Cell Stem Cell” This study found that hair shaft miniaturization in aging and genetic hypotrichosis leads to hair follicle stem cell loss through mechanical compression and apoptosis mediated by the Piezo1 channel.
This study suggests that finasteride may upregulate BTG2 and CD244 gene expression through differential methylation, indicating potential as a treatment avenue for medulloblastoma.
July 2025 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” In this study, researchers identified the miR-22-3p/CLIC4 signaling pathway as a key regulator in hair follicle miniaturization among androgenetic alopecia models, suggesting that targeting CLIC4-mediated sonic hedgehog pathway disruption may offer new therapeutic strategies for AGA treatment.
June 2021 in “International journal of research in dermatology” This report describes a child and his father with hereditary hypotrichosis simplex, an uncommon isolated form of hair loss, with no other ectodermal or systemic abnormalities noted.