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The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Women with PCOS have higher xanthine oxidase activity linked to inflammation and heart disease risks.

Glycoconjugates help heal hair follicles during skin repair.

Higher leptin levels link to hair loss.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

Women with PCOS often have mood disorders and a lower quality of life, and treatment should focus on both physical and mental health.

The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Understanding glycans and enzymes that alter them is key to controlling hair growth.

Most skin changes during pregnancy are harmless and temporary, but some can risk the fetus and need careful treatment.

FPHL causes hair loss in women due to genetics and hormones; minoxidil and anti-androgens are treatments, and early intervention is advised.

Non-immune factors play a significant role in alopecia areata.

The document says menstruation is important for women's health, discusses menstrual disorders, and suggests personalized treatment options.

The document concludes that more research is needed to fully understand the causes of PCOS.