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Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

Black ethnicity, prior PSA tests, enlarged prostate, and family history increase prostate cancer risk; Asian ethnicity, obesity, smoking, diabetes, and less sexual activity or no children decrease risk.

Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Some systemic treatments work for nail psoriasis but can have serious side effects.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Finasteride didn't significantly improve ICPPS symptoms, more research needed.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

LED therapy is safe and shows potential for treating skin conditions and promoting hair growth, but more research is needed.

Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).

Finasteride reduces Hidradenitis Suppurativa flare-ups in children and teens, but long-term safety is unknown.

Scalp cooling can reduce chemotherapy-induced hair loss and should be available in all hospitals.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Women with PCOS often experience anxiety, depression, and a lower quality of life.

Low-level laser therapy is safe and can increase hair growth for male and female pattern hair loss.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.