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The NUDT15 R139C variant causes thiopurine-induced leukocytopenia through a different mechanism than previously thought in Japanese patients with inflammatory bowel disease.

Genetic screening for NUDT15 polymorphisms is crucial for patients taking azathioprine, especially in Asians.

Hair loss in a child was an early sign of Crohn's disease.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

Budesonide is not effective for maintaining remission in Crohn's disease beyond three months.

A rare skin condition was confirmed to be associated with a specific virus in a young girl.

Anticancer drugs like methotrexate and trimetrexate could be effective and safe for treating malaria at low doses.

Azathioprine caused side effects in over half of the Korean pediatric inflammatory bowel disease patients, requiring close monitoring.

Chitosan-decorated finasteride nanosystems improve skin retention and could be a better treatment for hair loss.

Genetic testing is crucial before giving azathioprine to avoid severe side effects.

Pharmaceutical care in transplantation faces challenges but has promising future opportunities for better outcomes.

Low-dose chemotherapy is safer, more effective, and cost-effective than surgery for treating bone lesions in children.

Monitor for early signs of azathioprine toxicity and check blood counts regularly.

Cronkhite-Canada syndrome is rare, has a poor prognosis, and requires early diagnosis and ongoing treatment.

Docetaxel often causes hair loss, with limited effective treatments and no cure for permanent hair loss.

The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.

Various treatments exist for alopecia areata, but none are completely satisfactory; choice depends on age, disease extent, and preference.

Experts discussed treatments for skin conditions in children, emphasizing hydration, cautious medication use, and early intervention for infections.