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This study observed that adult Netherton syndrome patients showed a range of normal to diminished immune responses to polysaccharide, conjugate, and mRNA-based vaccines, with responses generally overlapping those of healthy controls, suggesting no consistent B- or T-cell immunodeficiency in this population.

In this review, researchers explored the multifaceted role of NF-κB signaling in various biological processes and diseases, including its interactions with other pathways, and discussed possible therapeutic approaches targeting this pathway for treating conditions like cancer, autoimmune disorders, and COVID-19.

This review highlights the potential of TCM medicinal foods for managing post-COVID disorders and suggests they could provide a safe and efficient long-term therapy due to their milder nature.

In this study, researchers found that Hdac1 and Hdac2 are crucial for maintaining the quiescence and survival of dermal papilla cells in the hair follicle, regulating the hair cycle by controlling cell-cycle genes and Wnt signaling.

This article reviews the role of nitric oxide in skin health, including its influence on immune responses and potential therapeutic applications for contact dermatitis, but reports no new clinical results.

In this study, researchers developed a rapid platform using primary human lung tissues to identify SARS-CoV-2 targets and test antiviral compounds, achieving highly reproducible results across viral variants.

In this study, GERD symptoms were found to be significantly related to acid exposure time and the intensity of excessive daytime sleepiness, which depends on circulating ghrelin levels.

This study found that Ift20 is essential for hair follicle stem cell identity and hair regrowth, and it regulates keratinocyte migration during wound healing through focal adhesion integrin recycling, independently of ciliogenesis.

This review examines the diversity and role of stem cells in the adult dermis, noting a lack of precise understanding about their hierarchy and relationship to dermal fibroblast subpopulations, and reports no new results.

This chapter reviews classic regeneration models in planarian worms and amphibian limbs, focusing on the role of stem cells, and reports no new experimental results.

This study found that young women with PCOS exhibited altered white matter microstructure and reduced cognitive performance compared to matched controls.

This review examines the impact of biotin, vitamin B12, and zinc on male reproduction, emphasizing their role in spermatogenic failure, but reports no new clinical results.

This chapter reviews secondary uses for various drugs, noting that some have regulatory approval, indicating verified safety and efficacy, while others lack approval despite strong evidence.

This article reviews a variety of research presentations from the Society for Investigative Dermatology's annual meeting, highlighting advances in dermatological research without reporting new clinical results.

Certain micronutrients may improve hair and nail health, but more research is needed to confirm their benefits.

This review discusses the advancements needed for gene therapy to become commonly used in dermatology and reports no new clinical results.

This study explores ear pinna development in mice and reports that elastic cartilage formation is disrupted in a short ear mutant, correlating with increased adult adipocytes and impaired chondrogenesis.

This review suggests that GABAergic neuroactive steroids modulated by alcohol could play a role in vulnerability to alcohol use disorders, providing a rationale for further therapeutic exploration.

This study found that in lamivudine-resistant hepatitis B patients, tenofovir significantly reduced HBV DNA levels faster and more consistently than adefovir, reaching undetectable levels in all treated patients by 44 weeks.

In this review, researchers summarize key factors in constructing skin organoids, including cell source and assembly methods, and emphasize advances such as air-liquid interface culture for improving tissue development, aiming to guide standardized protocols and future clinical applications.

This review discusses the dermatological and systemic adverse effects of hair dye use, particularly focusing on the common allergen para-phenylenediamine, and reports no new clinical data.

This review concluded that near-infrared and red light photobiomodulation shows potential for certain ocular conditions like age-related macular degeneration and dry eye disease, but clinical evidence is still mixed and insufficient to establish it as a standard therapy.

In this narrative review, the authors highlighted that AI-supported electronic health record analysis could help recognize Polycystic Ovary Syndrome/Polyendocrine Metabolic Ovarian Syndrome earlier, but also warned that these systems might perpetuate historical biases if not properly validated and interpreted.

This study found that HAMA hydrogels promote faster healing of skin wounds in mice by enhancing the accumulation of anti-inflammatory macrophages and increasing type III collagen in the local wound environment.

This study found that dedifferentiated corneal epithelial cells can revert to a stem-cell-like state, aiding tissue homeostasis and repair, with this plasticity limited to the epithelial lineage and enhanced by niche-derived cytokines.

In this study of Danioninae species, researchers reported that the presence of breeding tubercles on the pectoral fins is conserved in certain species and linked to local androgen conversion, with steroid 5-α-reductase playing a crucial role in their development.

This review outlines the major health consequences of anabolic-androgenic steroid abuse, with a focus on sexual and reproductive issues, and suggests management prioritizes cessation and relapse prevention due to lack of robust randomized trials.

This narrative review highlights the critical role of intracrine hormone production in peripheral tissues, suggesting that continuous-release subcutaneous testosterone pellet therapy may offer a more effective symptom-driven approach for aging populations, though large-scale randomized controlled trials are needed for confirmation.

In a conditional knockout mouse model, this study found that loss of the transcription elongation factor SPT6 in basal keratinocytes led to psoriasis-like skin inflammation and delayed wound healing, suggesting SPT6 plays a crucial role in maintaining epidermal immune quiescence by suppressing proinflammatory NF-κB signaling.

This study provides a framework for understanding different types of alopecias based on immune privilege collapse at specific follicular sites, revealing distinct patterns in immune effector programs and stromal influences depending on the alopecia type.