research The Hair Follicle as a Dynamic Mini-Organ
Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
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research Keratins in Health and Cancer: More Than Mere Epithelial Cell Markers
Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
research APCDD1 Is a Novel Wnt Inhibitor Mutated in Hereditary Hypotrichosis Simplex
A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
research Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology
Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
research Functional Salivary Gland Regeneration by Transplantation of a Bioengineered Organ Germ
Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.
research In Vitro and In Vivo Evaluation of Biologically Synthesized Silver Nanoparticles for Topical Applications: Effect of Surface Coating and Loading into Hydrogels
Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.
research Neural Mechanisms of Hair Growth Control
Nerves and chemicals in the body can affect hair growth and loss.
research Hormonal Regulation of Hair Follicles Exhibits a Biological Paradox
Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
research Lichen Planopilaris: Chronic Scarring Alopecia with Autoimmune Component
Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.
research White Lupin Cluster Root Acclimation to Phosphorus Deficiency and Root Hair Development Involve Unique Glycerophosphodiester Phosphodiesterases
White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.
research Beyond Expectations: The Role of Keratin Intermediate Filament Proteins in Epidermal Integrity
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research The Silver Locus Product (Silv/gp100/Pmel17) as a New Tool for the Analysis of Melanosome Transfer in Human Melanocyte–Keratinocyte Co-Culture
The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
research Role of S-Palmitoylation by ZDHHC13 in Mitochondrial Function and Metabolism in Liver
ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.
research Mechanisms of Hepatocyte Attachment to Keratin Biomaterials
Human liver cells stick to hair protein materials mainly through the liver's asialoglycoprotein receptor.
research Cultured Human and Rat Tooth Papilla Cells Induce Hair Follicle Regeneration and Fiber Growth
Tooth papilla cells can help regenerate hair follicles and grow hair.
research Hair Growth Induction: Roles of Growth Factors
EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
research Functional Hair Follicle Regeneration: An Updated Review
Hair follicle regeneration possible, more research needed.
research Azathioprine
Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
research Barley Disease Susceptibility Factor RACB Acts in Epidermal Cell Polarity and Positioning of the Nucleus
RACB in barley is crucial for cell polarity and nucleus positioning, aiding fungal infection.
research Update on the Dermatologic Use of Systemic Glucocorticosteroids
Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.
research Toxic Shock Syndrome: Recent Developments in Pathogenesis
Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.
research A Small Molecule Inhibitor Partitions Two Distinct Pathways for Trafficking of Tonoplast Intrinsic Proteins in Arabidopsis
Two distinct pathways direct proteins to vacuoles in Arabidopsis, affecting root hair growth and protein targeting.
research Divergent Neuroactive Steroid Responses to Stress and Ethanol in Rat and Mouse Strains: Relevance for Human Studies
Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.
research Severe Physical Complications Among Survivors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
SJS/TEN survivors often have severe, overlooked long-term physical problems that are not properly treated after leaving the hospital.
research The Effect of St. John's Wort on the Pharmacokinetics, Metabolism, and Biliary Excretion of Finasteride and Its Metabolites in Healthy Men
St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.
research Use of Extracellular Matrix Hydrogel from Human Placenta to Restore Hair-Inductive Potential of Dermal Papilla Cells
Human placenta hydrogel helps restore cells needed for hair growth.
research Structure of Human Steroid 5α-Reductase 2 with the Anti-Androgen Drug Finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
research Immune Modulation of Hair Follicle Regeneration
Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
research Identification of Transcriptional Targets of Wnt/β-Catenin Signaling in Dermal Papilla Cells of Human Scalp Hair Follicles: EP2 Is a Novel Transcriptional Target of Wnt3a
Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.
research Development and Prospects of Organ Replacement Regenerative Therapy
Scientists have made progress in creating replacement teeth, hair, and glands that work, which could lead to new treatments for missing teeth, baldness, and dryness conditions.