18 citations
,
April 1989 in “Archives of Dermatology” This study found that segmented heterochromic scalp hair associated with iron-deficiency anemia in a teenage girl completely recovered following iron supplementation, suggesting a role for iron in hair pigment production.
April 2025 in “Our Dermatology Online” This article presents a case of a seventeen-year-old female with dermatopathia pigmentosa reticularis and emphasizes the importance of distinguishing its clinical features from other similar disorders, supported by dermoscopic and histopathological findings.
10 citations
,
June 2009 in “Acta Biochimica Polonica” This study found that splenic melanosis in C57BL/6 mice is associated with synchronized skin melanization during hair cycles, but decreases with age.
April 2018 in “Journal of Investigative Dermatology” This study found that the cell of origin in mouse skin affects melanoma phenotype and response to therapies, despite the presence of the same genetic mutations.
25 citations
,
May 1995 in “Journal of the American Academy of Dermatology” This article reports two new cases of erythromelanosis follicularis faciei in women and includes a literature review on this rarely diagnosed condition.
July 2026 in “Our Dermatology Online” This study observed a significant rise and fall in black hair dye dermatitis cases over six years, primarily affecting middle-aged men, with most cases presenting as chronic pigmented lichenoid photodermatitis.
1 citations
,
January 2015 in “Journal of Pigmentary Disorders” This review discusses the complex relationship between melasma and factors like female sex hormones, genetics, and ultraviolet light exposure, but reports no new clinical findings.
401 citations
,
January 2013 in “Postepy Dermatologii I Alergologii” This review discusses the biology and development of skin melanocytes, but reports no new clinical findings.
9 citations
,
January 1975 in “Munich Personal RePEc Archive (Ludwig Maximilian University of Munich)” This report describes a case of Rothmund-Thomson type congenital poikiloderma, noting minor skin changes, hair loss, and slightly elevated lysine and cystine in the urine.
July 2025 in “Advanced Science” In this study, researchers discovered two new signaling pathways that regulate how melanocytes establish pigment patterns in reconstituted hair-bearing skin, offering insights that could inform strategies to prevent hair greying.
62 citations
,
October 2013 in “Journal of Human Evolution/Journal of human evolution” This review highlights the significance and future potential of forensic DNA phenotyping for predicting human phenotypes from crime scene DNA but reports no new results.
16 citations
,
February 2008 in “PubMed” Vitamin B12 deficiency can cause skin darkening and white hair, but it's reversible.
38 citations
,
February 2002 in “British journal of dermatology/British journal of dermatology, Supplement” This report describes two cases of sustained hair repigmentation related to porphyria cutanea tarda, though the underlying mechanism remains unclear.
April 2018 in “Journal of Investigative Dermatology” This study investigated novel genetic tools to manipulate hair follicle compartments in mice and found that altering dermal papilla genes can significantly impact hair pigmentation.
June 2025 in “British Journal of Dermatology” In this report, two cases of melanocytic matricoma, a rare benign hair follicle lesion that mimics melanoma and basal cell carcinoma, were described and successfully treated with complete surgical excision. Histological analysis was crucial for differentiation from similar malignant lesions.
This case report describes a pediatric instance of follicular atopic dermatitis in a dark-skinned patient, highlighting its unique clinical and dermoscopic features, such as purplish to brownish scaly papules and specific dermoscopic patterns, which are crucial for enhancing diagnostic accuracy in similar cases.
5 citations
,
February 2012 in “Australasian Journal of Dermatology” This case report documents two instances of red-haired men with patch-type alopecia areata, where hair regrowth occurred in black rather than red, an unusual phenomenon potentially linked to pigmentation and receptor pathways.
May 2021 in “GSC Advanced Research and Reviews” This review discusses recent advances in the understanding of follicular melanogenesis and its pathological changes, particularly how these changes are associated with specific disease phenotypes, but it reports no new results.
1 citations
,
September 2017 in “BMJ” The man has a disease causing skin patches, thickened nerves, and mild muscle weakness.
3 citations
,
March 2021 in “Cureus” This article reports a rare combination of rapid-onset halo nevi, nonsegmental vitiligo, and premature scalp hair graying.
75 citations
,
January 1980 in “Journal of Investigative Dermatology”
January 2024 in “International Journal of Herbal Medicine” This abstract describes the role of melanin in determining hair color and protecting against UV radiation, highlighting how its production affects hair health, growth, and vitality, with reduced production contributing to greying with age.
8 citations
,
June 2016 in “Journal of Cutaneous Pathology” This report describes two rare cases of desmoplastic melanoma presenting as alopecia neoplastica, highlighting a potential diagnostic pitfall for clinicians examining patients with scar-like alopecia.
January 1990 in “Springer eBooks” Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.
1 citations
,
June 2011 in “InTech eBooks” This review discusses the role of melanocytes in skin pigmentation and UV protection, explaining their interactions with keratinocytes and highlighting their involvement in processes like melanin transfer and melanoma development, but reports no new results.
18 citations
,
March 2015 in “Journal of Investigative Dermatology” In this study, silencing BMAL1 and PER1 genes increased melanogenic activity in follicular and epidermal melanocytes, suggesting that peripheral circadian clocks may regulate melanin pigmentation.
7 citations
,
March 2003 in “PubMed” This study reported that in men with androgenic alopecia, a distinct subclinical hyperpigmentation pattern was observed in the scalp, associated with baldness severity and possibly linked to local melanin production by pilosebaceous units.
4 citations
,
March 2020 in “JAAD Case Reports” This case report describes a 47-year-old male with rare total melanonychia linked to vitamin B12 deficiency, whose nail discoloration and constitutional symptoms improved following vitamin B12 supplementation.
450 citations
,
January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This article reviews follicular melanogenesis, detailing how melanin synthesis and its regulation in hair follicles depend on a complex interplay of cellular and molecular mechanisms, but reports no new clinical findings.
March 2026 in “Journal of Investigative Dermatology”