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SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.

Caffeine may protect hair follicles from stress-related hair loss.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

More research is needed before using brown fat to treat polycystic ovary syndrome.

Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.

Light affects skin health, aging, and cancer risk, and new light-based treatments and imaging are promising for skin care.

MC4R gene variants not linked to female hair loss.

Some medications can help increase sexual desire and function in women.

Hormonal treatments can improve acne, but they come with potential side effects and risks.

Black sheep have higher levels of Gnαs and Gnα11 proteins, which may affect their coat color.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

Lipase H is important for hair follicle function and shaping hair fibers.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

ACTH may be an effective first-line treatment for acute calcium pyrophosphate crystal arthritis.

Oral zinc sulphate reduces dark hair color in mice.

Older adults use lifestyle drugs to improve life quality and appearance, but caution is needed due to side effects and potential abuse.

PCOS has a strong genetic basis, but more research is needed to fully understand it.

BB4CMU rice bran oil may help treat hair loss and gray hair.

Anorexia Nervosa and Bulimia Nervosa are complex eating disorders with increasing incidence among young females, significant morbidity, and varying mortality rates, requiring more research for better treatment.

SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Certain foods and supplements can help treat skin diseases alongside medication.

Different genes cause Female Pattern Hair Loss compared to male hair loss, and treatments vary, but more research is needed to understand it fully.

Tocilizumab treatment was associated with significant hair regrowth in one patient and temporary hair loss followed by regrowth in another.

Compounds from certain trees used by First Nations people show potential for treating skin conditions and promoting hair growth, but more research is needed to confirm their safety and effectiveness.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.