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Skin's uneven surface and hair follicles affect its stress and strain but don't change its overall strength, and help prevent the skin from peeling apart.

KCNQ potassium channels help control the sensitivity of touch receptors in the skin.

The document suggests that nerve issues might contribute to hair loss and that testing sensation could predict these nerve problems.

Sensory neuron changes and Merkel-cell changes in the skin happen independently during normal skin maintenance.

Sensory neuron remodeling and Merkel-cell changes in the skin happen independently.

Sensory neuron remodeling and Merkel-cell changes happen independently during skin maintenance.

Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.

Sensory neurons and Merkel cells remodel at different rates during normal skin maintenance.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.

Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.

TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.

New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.

The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.

Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.

Botanical extract improved well-being and skin health in a test group compared to a placebo.

FGFR2 signaling controls Merkel cell formation in different skin regions.

Blond hair in Solomon Islanders is due to a unique genetic variant, not European ancestry.

Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.

Ptprq has multiple forms that change during inner ear development.

Melatonin may protect ear cells from damage caused by nicotine.

Zebrafish larvae are used to study and find treatments for ear cell damage because they are easier to observe and test than mammals.

Fermented soy protein may help prevent bone loss by affecting bone cell activity.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Different types of skin cells play specific roles in development, healing, and cancer.