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Reproductive gynecologists are the main referrers for male infertility evaluations in North America.

The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

Low doses of BPA can increase prostate growth and change hormone levels in adult rats.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Innovative methods are reducing animal testing and improving biomedical research.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.

Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.

Certain gene variations are not a major cause of male infertility in Nigerian men.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Zinc is important for growth and health in animals, plants, and humans, and not having enough can cause various problems.

The right dosage of CPA and TB can work as a safe and reversible male contraceptive in monkeys.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

Finasteride 1-mg doesn't harm sperm or pregnancy chances.

American men are older, more obese, and have longer infertility than Canadian men.

Losing weight, fixing varicoceles, and using advanced sperm selection methods improve male infertility treatment outcomes.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

Omega-6 fats in certain cells boost male hormone production.

Toxoplasma gondii infection may increase testosterone levels in males.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Some medications might contribute to male infertility, with finasteride showing a high number of reports.