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Nude mice with grafted human skin developed scars similar to human hypertrophic scars.

α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

Iron deficiency may contribute to hair loss.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

The study found that combining different databases gives a better estimate of drug side effects in hospitals.

Bergamot may improve heart health, skin conditions, and mood, but more research is needed to confirm these benefits.

Leflunomide and methotrexate are equally effective for rheumatoid arthritis but have different side effects.

Cell aging can be both good and bad for tissue repair.

Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.

Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

Skin organoids are a promising new model for studying human skin development and testing treatments.

The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

Oral zinc sulphate reduces dark hair color in mice.

Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.

Enzyme purified and characterized for minoxidil sulphation in rat liver.

Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.

Monochromatic light devices, especially the 308-nm excimer laser, are promising for treating alopecia areata but more research is needed.

The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.