research Exogen, Shedding Phase of the Hair Growth Cycle: Characterization of a Mouse Model
Researchers found that hair shedding happens mostly when new hair is growing and involves a unique process.
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research Immunohistochemical Localization of Types 1 and 2 5α-Reductase in Human Scalp
The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.
research Prolactin and Its Receptor Are Expressed in Murine Hair Follicle Epithelium, Show Hair Cycle-Dependent Expression, and Induce Catagen
Prolactin affects hair growth cycles and can cause early hair follicle regression.
research Polycystic Ovarian Syndrome: Comprehensive Overview and Management Approaches
Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.
research Simple and Rapid Method to Isolate and Culture Follicular Papillae from Human Scalp Hair Follicles
Researchers developed a quick and easy way to get and grow cells from the base of human hair follicles.
research Methotrexate in Dermatology
Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.
research Expression of Calcium-Binding S100 Proteins A4 and A6 in Regions of the Epithelial Sac Associated with the Onset of Hair Follicle Regeneration
S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.
research P53 Involvement in the Control of Murine Hair Follicle Regression
The p53 protein helps control hair follicle shrinking by promoting cell death in mice.
research What Women Want: Quantifying the Perception of Hair Amount - An Analysis of Hair Diameter and Density Changes with Age in Caucasian Women
Caucasian women's hair appears thickest in their 20s, with perceived thinning after mid-30s due to both decreasing density and diameter.
research The Role of Lymphocytes in the Development and Treatment of Alopecia Areata
Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
research Physiological Regeneration of Skin Appendages and Implications for Regenerative Medicine
The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
research A Position Effect on TRPS1 Is Associated with Ambras Syndrome in Humans and the Koala Phenotype in Mice
A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.
research Baldness And The Androgen Receptor: The AR Polyglycine Repeat Polymorphism Does Not Confer Susceptibility To Androgenetic Alopecia
AR polyglycine repeat doesn't cause baldness.
research Unmet Medical Needs in Chronic, Non-Communicable Inflammatory Skin Diseases
There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
research Cyclosporin A-Induced Hair Growth in Mice Is Associated with Inhibition of Calcineurin-Dependent Activation of NFAT in Follicular Keratinocytes
Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.
research Loose Anagen Hair as a Cause of Hereditary Hair Loss in Children
Loose Anagen Hair Syndrome is a hereditary condition causing hair loss in children due to abnormal hair follicles.
research Significance of the Polyglutamine Tract Polymorphism in the Androgen Receptor
The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.
research Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes
People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
research Selected Disorders of Skin Appendages: Acne, Alopecia, Hyperhidrosis
The conclusion is that acne, alopecia, and hyperhidrosis are common skin issues with various treatments available, and accurate diagnosis is key for effective management.
research Repairing the Lungs One Breath at a Time: How Dedicated or Facultative Are You?
Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
research Minoxidil
Minoxidil controls blood pressure effectively, but may cause side effects like hypertrichosis.
research Malignancy and Cancer Treatment-Related Hair and Nail Changes
Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.
research Toward a Diagnostic Score in Cushing's Syndrome
The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.
research Spinal and Bulbar Muscular Atrophy: Pathogenesis and Clinical Management
Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.
research Trichoscopy
Trichoscopy is a useful tool for diagnosing different hair and scalp diseases without surgery.
research Effect of Ethnicity and Treatments on In Situ Tensile Response and Morphological Changes of Human Hair Characterized by Atomic Force Microscopy
Different ethnicities and treatments affect human hair strength and structure.
research The Biology of Hair Care
Better hair care products are needed to protect against grooming and chemical damage.
research 5α-Reductase Activity in the Human Hair Follicle Concentrates in the Dermal Papilla
The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
research Hair Darkening in Porphyria Cutanea Tarda
Two patients with porphyria cutanea tarda experienced their grey hair turning dark again.
research Trichoscopic Clues for Diagnosis of Alopecia Areata and Trichotillomania in Asians
Trichoscopy helps tell apart alopecia areata and trichotillomania in Asians by looking at specific hair and scalp features.