January 2026 in “Forum Dermatologicum” This review examines various pharmacological options for managing alopecia areata, highlighting the effectiveness of corticosteroids for mild to moderate cases and promising results from JAK inhibitors like baricitinib for more severe forms, with additional benefits from minoxidil and potential from other treatments.
July 2024 in “Journal of Investigative Dermatology” Tailored treatments for alopecia areata show promising results, with pulse steroids effective for mild cases and Ritlecitinib, Dupilumab, or methotrexate and prednisone effective for severe cases.
June 2020 in “AACE clinical case reports” This case report illustrates that Leydig cell tumors, despite causing significantly elevated androgen levels, can be difficult to localize due to their small size, as demonstrated in a 42-year-old woman whose tumor was only identified after oophorectomy.
July 2025 in “Russian Journal of Clinical Dermatology and Venereology” This review discusses the multifactorial nature and treatment of alopecia areata, highlighting its prevalence among adolescents and the necessity for comprehensive diagnostic and therapeutic approaches, but reports no new empirical findings.
2 citations
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November 2019 in “Cancer reports” This study concluded that the Wnt signaling pathway does not significantly influence human keratoacanthoma development, but the overexpression of Sox9 suggests alternate signaling involvement.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study describes alopecia areata as a long-term, immune-mediated disorder characterized by non-scarring hair loss, often occurring in genetically predisposed individuals and possibly triggered by T-cell-mediated inflammation, environmental stressors, and genetic factors.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study explains that alopecia areata, a long-term immune-mediated disorder causing patchy baldness, results from an immunological attack on hair follicles, often in genetically predisposed individuals, with a complex mix of immunological, environmental, and genetic factors involved in its development.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This source explores alopecia areata, an immune-mediated disorder causing patchy hair loss due to immunological attacks on hair follicles, with a complex interaction of genetic, environmental, and immunological factors, particularly T-cell-mediated inflammation, contributing to its onset.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this research, the authors describe alopecia areata as a long-term, immune-mediated disorder that causes non-scarring hair loss due to an immunological attack on hair follicles, often occurring in genetically predisposed individuals and manifesting in childhood or early adulthood.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This abstract explains that alopecia areata is an immune-mediated condition causing non-scarring hair loss, typically in genetically predisposed individuals, with its etiology linked to immune dysregulation, environmental stressors, and genetic factors.
36 citations
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May 2011 in “Dermatologic therapy” This review discusses topical and intralesional treatments for alopecia areata, providing a management strategy based on patient age and disease severity, but reports no new clinical results.
March 2026 in “Actas Dermo-Sifiliográficas” This consensus document, developed by 23 dermatologists using a Delphi method, aims to guide the management of alopecia areata by providing structured recommendations for various stages of the condition, following expert opinion and scientific evidence.
In a proof-of-concept study at Xiangya Hospital, the researchers observed that combining tofacitinib with low-dose interleukin-2 helped maintain remission in refractory alopecia areata patients, with three out of four maintaining complete remission for 11–20 months post-treatment and no adverse events reported.
3 citations
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April 2012 in “Cancer research” This study reports that side-population stem cells, distinct from hair follicle stem cells, may play a significant role in the malignant progression of squamous cell carcinomas in mice.
April 2010 in “Cancer Research” This study suggests that Mcl-1 has a non-apoptotic role in promoting keratinocyte proliferation and Wnt/β-catenin signaling, potentially indicating a novel oncogenic activity.
14 citations
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March 2014 in “Acta anaesthesiologica Taiwanica” This report presents a case of Tapia's syndrome and pressure alopecia occurring simultaneously after open septorhinoplasty, emphasizing the need for awareness of these complications among anesthesiologists and surgeons.
This comparative clinical study found no statistically significant difference in the remission and recurrence rates between intralesional triamcinolone acetonide and methotrexate for treating localized alopecia areata, suggesting similar efficacy between the two treatments.
18 citations
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October 2014 in “Experimental Biology and Medicine” This study found that feeding mice high levels of dietary vitamin A increased WNT signaling, which activated hair follicle stem cells and may have accelerated alopecia areata progression.
March 2026 in “Journal of Sustainable Veterinary and Allied Sciences” In this case report, a 5-year-old female German shepherd diagnosed with canine babesiosis and ehrlichiosis fully recovered after receiving parenteral treatment for these infections and topical therapy for dermatitis at the University of Ilorin's Veterinary Teaching Hospital.
April 2024 in “Dermatology and therapy” This study surveyed dermatologists in Greece and Italy and found significant variability and challenges in the diagnosis and treatment of alopecia areata, including limited use of severity scores and diverse treatment approaches, particularly for special site involvement and chronic cases.
98 citations
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June 2008 in “Human mutation” This study found that a genetic variant in the EDAR gene leads to typical East Asian hair characteristics by increasing signaling output, as shown in transgenic mice experiments.
53 citations
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January 2017 in “Skin appendage disorders” This review discusses botulinum toxin's experimental off-label uses in dermatology, highlighting promising results but emphasizing the need for more clinical trials to confirm efficacy and safety.
50 citations
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March 2021 in “Journal of investigational allergology & clinical immunology” This review examines existing research and clinical trials on the use of dupilumab for various skin, respiratory, and gastrointestinal disorders, but it reports no new clinical findings.
25 citations
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June 2013 in “Obesity Reviews” This review examines mesotherapy for local fat reduction, detailing its mechanisms, safety concerns, and the need for research toward FDA-approved uses, but reports no new clinical findings.
16 citations
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July 2002 in “Australasian Journal of Dermatology” This case report illustrates the risk of skin necrosis in patients with high antiphospholipid antibody levels after stopping anticoagulation therapy, highlighting the necessity for careful monitoring.
11 citations
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September 2012 in “Journal of Nanjing Medical University” In this study, cyclosporine A stimulated hair growth in mouse vibrissae organ culture by promoting matrix cell proliferation and altering growth factor expression.
8 citations
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October 2019 in “Immunological investigations” This study suggests that the rs2075876 variant in the AIRE gene may significantly increase susceptibility to alopecia areata in the examined male population.
4 citations
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May 2021 in “Biomedicines” This review explores the potential role of caveolin-1 in cicatricial alopecia, particularly frontal fibrosing alopecia, and discusses possibilities for targeted therapies without providing new research results.
2 citations
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July 2020 in “Journal of Applied Pharmaceutical Science” This study examined the preservative and antimicrobial susceptibility of non-fermenting bacilli collected from beauty salon waste in Brazil.
November 2025 in “The Journal of Medical Sciences” This article reviews the potential and limitations of cryotherapy for alopecia areata in middle-aged patients and highlights the need for further research, without reporting new clinical findings.