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This review highlights the potential of drug-loaded extracellular vesicles as a promising drug delivery platform but notes that clinical translation faces challenges due to variability in methods and the need for standardization and safety evaluation.

This study highlights IGF-1's role in promoting hair follicle proliferation, vascularization, and growth, suggesting its potential as a treatment target for hair loss disorders like androgenetic alopecia, though more research on delivery methods and long-term effects is needed.

This review discusses the potential of novel delivery systems to improve the bioavailability and therapeutic effects of herbal bioactives in colorectal cancer treatment.

This study found that in androgenetic alopecia mice, MNX@Arg-CLAVs, a novel nanovesicle platform containing minoxidil and conjugated linoleic acid, enhanced hair regeneration and reduced hair follicle aging more effectively and with less irritation compared to traditional minoxidil tincture.

This review discusses the potential of platelet-rich plasma applications in regenerative medicine and explores recent progress and challenges in translating non-clinical PRP findings into human treatments, but reports no new clinical results.

This review discusses factors affecting hair aging and the current pharmacological treatments for androgenetic alopecia, mentioning topical minoxidil and oral finasteride, but does not present new clinical findings.

This review summarizes recent progress in microneedle-based drug delivery systems and discusses their potential impact on cellular mechanisms and immunization signaling pathways, highlighting the need for further development in fabrication methods.

This paper reviews strategies to enhance the effectiveness of topical drug delivery by addressing skin barrier challenges, optimizing drug delivery systems, and personalizing treatment approaches, highlighting both current advancements and limitations in the field.

This study found that melatonin-loaded vitamin C-based nanovesicles improved hair thickness, density, and reduced hair loss in patients with androgenic alopecia more effectively than melatonin solution.