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    Glossary Lipodystrophy

    abnormal fat distribution in the body

    Lipodystrophy is a medical condition characterized by abnormal or degenerative conditions of the body's adipose (fat) tissue. It can manifest as either the loss of fat (lipoatrophy) or abnormal accumulation of fat in certain areas. This condition can be genetic or acquired and is often associated with metabolic complications such as insulin resistance and diabetes.

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    1. How to diagnose a lipodystrophy syndrome Annales d'Endocrinologie · 2012 · 53 citations
    2. Biological Features Implies Potential Use of Autologous Adipose-Derived Stem/Progenitor Cells in Wound Repair and Regenerations for the Patients with Lipodystrophy International Journal of Molecular Sciences · 2019 · 23 citations
    3. A 10 Mb duplication in chromosome band 5q31.3–5q33.1 associated with late-onset lipodystrophy, ichthyosis, epilepsy and glomerulonephritis European Journal of Medical Genetics · 2011 · 5 citations
    4. Impact of Combined Baricitinib and FTI Treatment on Adipogenesis in Hutchinson–Gilford Progeria Syndrome and Other Lipodystrophic Laminopathies Cells · 2023 · 4 citations
    5. Treatment of Lipodystrophy with Troglitazone Annals of Internal Medicine · 2001 · 1 citations
    6. Loss of adipocyte phospholipase gene PLAAT3 causes lipodystrophy and insulin resistance due to inactivated arachidonic acid-mediated PPARγ signaling 2021
    7. Dunnigan-Type Familial Partial Lipodystrophy: Understanding and Treating the Syndrome Open Journal of Endocrine and Metabolic Diseases · 2017
    8. Centrifugal lipodystrophy of the scalp manifesting as centrifugal lipodystrophic alopecia Clinical and Experimental Dermatology · 2017 · 3 citations
    9. Metreleptin Treatment in a Boy with Congenital Generalized Lipodystrophy due to Homozygous c.465_468delGACT (p.T156Rfs*8) Mutation in the BSCL2 Gene: Results From the First-year JCRPE · 2022 · 1 citations
    10. MON-194 A Case Of Sertoli Cell Tumor In A Patient With Familial Partial Lipodystrophy Type 2 Journal of the Endocrine Society · 2025
    11. Progressive Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) from a Young Age Due to a Rare Genetic Disorder, Familial Partial Lipodystrophy: A Case Report and Review of the Literature Livers · 2024
    12. Anterior neck fat deposition in lipodystrophy syndrome; a new variant on a theme? AIDS · 2003 · 5 citations
    13. Atypical Progeroid Syndrome due to Heterozygous Missense LMNA Mutations 2009 · 115 citations
    14. Peroxisome proliferator-activated receptors (PPARs) and PPAR agonists: the ‘future’ in dermatology therapeutics? Archives of dermatological research · 2015 · 60 citations
    15. Adverse Drug Reactions in HIV/AIDS Patients on Highly Active Antiretro Viral Therapy: A Review of Prevalence NEWPORT INTERNATIONAL JOURNAL OF SCIENTIFIC AND EXPERIMENTAL SCIENCES · 2023 · 24 citations
    16. The metabolic syndrome- associated small G protein ARL15 plays a role in adipocyte differentiation and adiponectin secretion Scientific Reports · 2017 · 23 citations
    17. Tissue fibrosis associated depletion of lipid‐filled cells Experimental Dermatology · 2024 · 6 citations
    18. Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice GeroScience · 2025 · 4 citations
    19. Hutchinson-Gilford progeria syndrome: Report of 2 cases and a novel LMNA mutation of HGPS in China Journal of the American Academy of Dermatology · 2013 · 3 citations
    20. A rare LMNA missense mutation causing a severe phenotype of mandibuloacral dysplasia type A: a case report Revista Paulista de Pediatria · 2024 · 2 citations
    21. Progeria (Hutchinson-Gilford Syndrome): Literature Review and Clinical Case Вопросы современной педиатрии · 2022 · 1 citations
    22. Author response: Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression 2017 · 1 citations
    23. The transcription elongation factors Spt4 and Spt6 promote dermal adipocyte differentiation Adipocyte · 2026
    24. Case report: A novel splice-site mutation of MTX2 gene caused mandibuloacral dysplasia progeroid syndrome: the first report from China and literature review Frontiers in endocrinology · 2024
    25. Decision letter: Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression 2017
    26. Skin disorders in diabetes mellitus Journal der Deutschen Dermatologischen Gesellschaft · 2014
    27. Syndromes of Severe Insulin Resistance (SSIRs) 2004
    28. Diabetes and Skin — A Review Scottish medical journal · 1974 · 24 citations
    29. Treatment of acne with intermittent isotretinoin, cohort study 1998
    30. Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome Frontiers in endocrinology · 2020 · 29 citations