September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a mutation in the CST6 gene linked to a rare syndrome with symptoms affecting hair and skin, revealing cystatin M/E's role in maintaining epidermal homeostasis and hair follicle development.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that in a mouse model of Focal Dermal Hypoplasia, treatment with lithium carbonate improved skin disease symptoms compared to controls, though disease severity varied and posed interpretation challenges.
9 citations
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January 2023 in “International Journal of Biological Sciences” This study suggests that CTHRC1, a protein expressed in cardiac fibroblasts, may improve wound repair and prevent cardiac rupture after myocardial infarction by activating a specific signaling pathway.
31 citations
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July 2012 in “Journal of Lipid Research” This study found that the acyl-CoA binding protein is essential for the production of very long chain free fatty acids in the stratum corneum and maintaining normal epidermal barrier function in mice.
December 2022 in “Frontiers in plant science” This study identifies two new proteins, CCDC22 and CCDC93, essential for root and root hair growth in Arabidopsis, and demonstrates their genetic link to a VTI13-dependent vacuolar trafficking pathway.
July 2026 in “Journal of Investigative Dermatology” August 2009 in “Mechanisms of Development”
6 citations
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October 2017 in “Oncotarget” In this study, NIH hairless mice showed increased susceptibility to Listeria monocytogenes infection compared to NIH mice, potentially due to differences in gut microbiota and monocyte levels.
CaBP1 and CaBP2 are important for continuous hearing by preventing inactivation of calcium currents in ear cells, with CaBP2 also able to restore hearing when reintroduced.
1 citations
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January 2021 in “Journal of the American Academy of Dermatology” This study found that bullous lupus erythematosus lesions in cutaneous lupus erythematosus showed distinctive histopathology with neutrophilic predominance and were associated with severe disease and higher extracutaneous involvement.
September 2008 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Loss of Dsc3 function in the epidermis impaired cell adhesion, leading to blistering and hair loss, which suggests a potential cause of PV-like skin diseases according to this study.
CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.
10 citations
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November 2018 in “Genetics in medicine” This study identified a genetic variant in the CTS6 gene associated with a hypotrichosis syndrome, emphasizing the significant role of cystatin M/E in hair and skin health.
66 citations
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October 2002 in “Human molecular genetics online/Human molecular genetics” This study found that a nonsense mutation in the Cst6 gene of mice leads to severe skin and hair abnormalities, suggesting that cystatin M/E is crucial for epidermal function and viability.
13 citations
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November 1995 in “European Archives of Oto-Rhino-Laryngology” This abstract lists numerous dermatological side effects and reactions associated with various medications but reports no new research findings.
November 2025 in “Journal of Investigative Dermatology” Skin-associated cartilage cells can influence hair growth by altering specific signaling pathways.
36 citations
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March 2014 in “Molecular and Cellular Biology” This study found that Cidea is critical for regulating lipid storage and sebum secretion in sebaceous glands, with its deficiency causing hair issues and impaired skin functions in mice.
26 citations
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April 2021 in “Materials & Design” This study found that composite chitosan nanofibers containing luminescent europium complexes can sensitively detect Cu2+ concentrations as low as 10 μmol/L, making them suitable for use in biological systems.
3 citations
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January 2025 in “Journal of Natural Products” In this study, researchers isolated new compounds from the plant *Calanthe cardioglossa* and found that five of these compounds, particularly calancardin B, significantly reduced TNF-α levels in immune cells relevant to multiple sclerosis, suggesting potential for immunomodulatory effects.
July 2024 in “Journal of Investigative Dermatology” Patients with cutaneous lupus erythematosus have a higher risk of skin cancer and other cancers.
56 citations
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April 2019 in “The Plant Journal” This study found that CNGC 6, CNGC 9, and CNGC 14 are crucial for maintaining calcium oscillations necessary for normal root hair growth in plants, with mutations leading to defects like swelling and bursting.
7 citations
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May 1978 in “Acta Dermato Venereologica” This case report details a 36-year-old man with atypical necrobiosis lipoidica on his face, characterized by annular lesions and prominent giant cells without clear granuloma formation.
67 citations
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February 2022 in “International Journal of Molecular Sciences” This study developed a nanofiber wound dressing combining ciprofloxacin and tetracycline hydrochloride, which demonstrated strong antibacterial activity against E. coli and S. aureus and showed good biocompatibility with human skin fibroblast cells, indicating significant potential for wound healing applications.
April 2024 in “Canadian Journal of Ophthalmology” The authors report that a 62-year-old woman with invasive conjunctival squamous cell carcinoma experienced complete remission two years after combining cemiplimab, retinoic acid, and IFNα-2b treatments, highlighting potential utility despite limited availability of IFNα-2b.
1 citations
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April 2019 in “Journal of Investigative Dermatology” This study concluded that the topical gel VB1953 reduced inflammatory and non-inflammatory acne lesions and resistant bacteria in patients with clindamycin-resistant acne, showing promise as an effective treatment.
August 2012 in “Nature Cell Biology” In this study, researchers found that β-catenin directly promotes TERT expression in stem and cancer cells by interacting with the Tert promoter, illustrating a mechanistic link between tumorigenesis and pluripotency.
3 citations
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October 2011 This article discusses revised SLE classification criteria by the SLICC and reports no new research results.
7 citations
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June 2009 in “Journal of the European Academy of Dermatology and Venereology” This study found that in lichen planopilaris, the basement membrane zone of the hair follicles exhibited disrupted and discontinuous staining patterns, potentially contributing to scarring and irreversible hair loss.
4 citations
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April 2016 in “Journal of The American Academy of Dermatology” This case report details the first known instance of interferon-induced lichen planus in a seronegative HCV patient with metastatic renal cell carcinoma.