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This study found that autophagy is impaired in Birt-Hogg-Dubé syndrome-associated renal tumors and identified that the FLCN protein interacts with key autophagy components regulated by ULK1.

Certain NK cell changes in blood may indicate alopecia areata progression.

This review explores clinical studies on low-level laser therapy (LLLT) for alopecia and suggests it may benefit patients unresponsive to conventional treatments, but larger studies are needed to confirm efficacy.

This case report describes a patient with primary cutaneous natural killer/T-cell lymphoma, nasal type, where monoclonal Epstein–Barr virus genome expansion was associated with terminal aggressive behavior after an indolent clinical course.

This review discusses the benefits and applications of low level laser therapy in cosmetic dermatology, particularly for skin conditions and pigmentation disorders, but reports no new clinical results.

This report details a case of a 3-year-old child with Clouston syndrome, a rare inherited disorder affecting nails, skin, and hair, highlighting the need for supportive management due to the absence of treatment options.

This study found that conditional deletion of CD271 in mouse epidermis led to significant disorganization and increased thickness, suggesting CD271's crucial role in regulating skin differentiation and structure.

Cathepsin L deficiency causes hair and skin issues in mice.

This review discusses the complexity and genetic organization of human keratin gene clusters and addresses the ongoing need for an updated unified naming system; it reports no new clinical results.

In this study, researchers identified two de novo germline missense mutations in the hair keratins hHb1 and hHb6 in patients with monilethrix whose parents were not clinically affected.

This study found that the absence of laminin α5 in adult mice's epidermal basement membrane led to keratinocyte hyperproliferation and immune cell changes, affecting hair follicle development through altered growth factor expression.

This study found that unique genomic regions in Korean long-tailed chickens may contribute to their long tail feathers, offering potential for genetic advancements in ornamental chicken breeding.

This study developed a mouse model lacking keratin 16 to replicate palmoplantar lesions, which may help uncover the molecular mechanisms driving these lesions in pachyonychia congenita and focal non-epidermolytic palmoplantar keratoderma.

This review synthesizes the diverse roles of the transcription factor LHX2 in development, tissue maintenance, and injury repair across various organ systems, highlighting its potential therapeutic applications and significance in regenerative medicine, particularly in developmental disorders and tissue regeneration.

This article describes a non-blinded study investigating low level laser therapy for seven patients but reports no new clinical findings.

This study found that NGAL expression in embryonic skin is spatio-temporally regulated and strongly induced in adult skin conditions with dysregulated differentiation, suggesting a role in epithelial differentiation pathways.

K39 and K40 are the last keratins expressed in hair development, completing the hair keratin catalog.

In this study, PINCH-1 gene loss in mouse epidermis led to detachment from the basement membrane, thickened skin, and hair loss, with findings suggesting PINCH-1 plays a role in keratinocyte adhesion through both ILK and EPLIN pathways.

This study found that long pulsed Nd-YAG laser treatment significantly improved acne keloidalis nuchae by reducing inflammation and hair follicles, with early intervention yielding the best results.

This study identified a new type II cytokeratin, named K6hf, exclusively expressed in the companion layer of the human hair follicle, distinguishing it from other keratins and suggesting a unique biochemical role.

This review highlights that light and laser therapies, such as the 1064-nm Nd:YAG and 810-nm diode lasers, may offer significant improvement for acne keloidalis nuchae with minimal side effects, though larger trials are needed.

This study developed a kidney-specific knockout mouse model lacking the Flcn gene, which recapitulates human Birt-Hogg-Dubé kidney tumorigenesis and shows that mTOR pathway inhibition with rapamycin can suppress tumor growth.

This study found that a mutation in the seventh exon of the KRT86 gene plays a major role in the pathogenesis of monilethrix in a Chinese family.

A specific RNA increases hair stem cell growth and skin healing by affecting a protein through interaction with a microRNA.

This study found that keratin expression patterns vary within nail unit structures, with the nail matrix uniquely expressing the acidic hair-type keratin Ha1.

This study found that elevated luteinizing hormone levels were significantly associated with female pattern hair loss, and implicated LH/LHR signaling in the aging and damage of hair follicles.

This review discusses the effects of low-level laser therapy in various biological processes for wound healing and tissue repair and reports no new results.