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    Did you mean Keratinocyte Growth Factor?
    Glossary Keratinocyte Growth Factor

    stimulates skin and hair cell growth and repair

    Keratinocyte Growth Factor (KGF), also known as Fibroblast Growth Factor 7 (FGF-7), is a protein that plays a crucial role in the growth and repair of skin and hair. It specifically stimulates the proliferation and differentiation of keratinocytes, which are the primary cells found in the outer layer of the skin and hair follicles. This makes KGF important in wound healing and potentially beneficial in treating conditions like alopecia.

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    Research 30 of 1000+

    1. Research progress and strategies for the biosynthesis of keratinocyte growth factor-2 (KGF-2) in <i>Arabidopsis thaliana</i> PeerJ · 2025
    2. Effects of recombinant human keratinocyte growth factor-2 on hair regeneration in experimental bald rats 2012
    3. trans-3,4'-Dimethyl-3-hydroxyflavanone, a Hair Growth Enhancing Active Component, Decreases Active Transforming Growth Factor .BETA.2 (TGF-.BETA.2) through Control of Urokinase-Type Plasminogen Activator (uPA) on the Surface of Keratinocytes Biological and Pharmaceutical Bulletin · 2008 · 10 citations
    4. Transforming Growth Factor-??, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes Plastic and Reconstructive Surgery · 2007 · 16 citations
    5. l-Ascorbic acid 2-phosphate promotes elongation of hair shafts via the secretion of insulin-like growth factor-1 from dermal papilla cells through phosphatidylinositol 3-kinase 2009 · 34 citations
    6. Growth factor mimetics for skin regeneration: In vitro profiling of primary human fibroblasts and keratinocytes Archiv der Pharmazie · 2021 · 3 citations
    7. Corticotropin-Releasing Factor Down-Regulates Hair Growth-Related Cytokines in Cultured Human Dermal Papilla Cells Journal of the Society of Cosmetic Scientists of Korea · 2014 · 1 citations
    8. Hair-Growth-Promoting Effect of Conditioned Medium of High Integrin α6 and Low CD 71 (α6bri/CD71dim) Positive Keratinocyte Cells International Journal of Molecular Sciences · 2015 · 17 citations
    9. Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22 PLOS Genetics · 2015 · 52 citations
    10. Hair growth stimulated by conditioned medium of adipose-derived stem cells is enhanced by hypoxia: evidence of increased growth factor secretion Biomedical research · 2010 · 134 citations
    11. 1049 Novel strategy to promote hair follicle growth and stem cell activation in human male scalp skin: Targeting prolactin receptor with ABS-201 Journal of Investigative Dermatology · 2026
    12. 216 Human hair follicles can “smell”: OR2AT4-mediated hair growth regulation Journal of Investigative Dermatology · 2016
    13. Induction of Hair Growth by Insulin-Like Growth Factor-1 in 1,763 MHz Radiofrequency-Irradiated Hair Follicle Cells PLoS ONE · 2011 · 39 citations
    14. The Role of Moracin M in Promoting Hair Growth: Insights into Mechanisms of WNT/β- Catenin Pathway Activation and Angiogenesis Enhancement in Human Dermal Papilla Cells Research Square (Research Square) · 2024
    15. Keratinocyte Cytokine Networks Associated with Human Melanocytic Nevus Development Journal of Investigative Dermatology · 2018 · 5 citations
    16. The Experimental Studies of YangHyulEum Gami-Bang Extracts on the Hair Growth Effect Hanbang an'i'bi'in'hu pibu'gwa haghoeji · 2016 · 1 citations
    17. ROCK inhibitor Y-27632 maintains the propagation and characteristics of hair follicle stem cells. PubMed · 2018 · 12 citations
    18. Depletion of <i>Gsdma1/2/3</i> alleviates PMA-induced epidermal hyperplasia by inhibiting the EGFR–Stat3/Akt pathway Journal of Molecular Cell Biology · 2023 · 6 citations
    19. Role of Dermal Factors Involved in Regulating the Melanin and Melanogenesis of Mammalian Melanocytes in Normal and Abnormal Skin International journal of molecular sciences · 2024
    20. Strengthening the Skin with Topical Delivery of Keratinocyte Growth Factor-1 Using a Novel DNA Plasmid Molecular Therapy · 2014 · 23 citations
    21. Keratinocyte Growth Factor Modified Messenger RNA Accelerating Cell Proliferation and Migration of Keratinocytes Nucleic Acid Therapeutics · 2018 · 11 citations
    22. Effect of <i>Ficus carica</i> leaf extract on the gene expression of selected factors in HaCaT cells Journal of Cosmetic Dermatology · 2017 · 16 citations
    23. Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts Journal of dermatological science · 2019 · 20 citations
    24. 28-Year-Old Female with Diffuse Thinning of the Scalp after Isotretinoin and Oral Contraceptives Clinical Cases in Dermatology · 2022
    25. Abstract 2559: Targeting mTORC1 may provide selectivity for inhibiting proliferation of hair follicle stem/progenitor cells during tumor promotion Cancer research · 2012
    26. Possible Cellular Communication with Human Follicle Dermal Papilla Cells via Secretions from Human Hair Follicle Keratinocytes Journal of St. Marianna University · 2022
    27. A ‘hot’ new twist to hair biology – involvement of vanilloid receptor‐1 signaling in human hair growth control Experimental Dermatology · 2004 · 2 citations
    28. LB1604 The role of polyunsaturated fatty acids on hair growth Journal of Investigative Dermatology · 2018
    29. Phosphatidic Acid Has a Potential to Promote Hair Growth In Vitro and In Vivo, and Activates Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase in Hair Epithelial Cells 2003 · 46 citations
    30. Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation The Journal of Clinical Endocrinology & Metabolism · 2008 · 115 citations